Mr Chris Bretherton, BMedSci, BMBS (Hons), DPhil, FRCS (Orth)

Profile

Chris as an NIHR Academic Clinical Lecturer and Specialty Registrar (SpR) in Trauma and Orthopaedic Surgery at Queen Mary University London and the Royal London Hospital Rotation. Prior to this he studied medicine at the University of Nottingham, graduating with honours. He completed his foundation training in the North Central Thames region and his core training in the east of England Deanery. He commenced his higher surgical training in Oxford in 2015 and in 2023 earned his Doctor of Philosophy (DPhil) degree from the University of Oxford, before moving back to London to join the Barts Bone and Joint Health team.

He has a passion for collaborative research, with a portfolio which includes multi-centre audits, randomized controlled trials, and priority setting partnerships (PSP). His expertise spans systematic reviews, clinical trials, and mixed-methods research.  His collaborations with institutions like the Royal College of Surgeons and the British Orthopaedic Trainees Association (BOTA) have facilitated surgeon involvement in multi-center clinical trials. As the past Academic Representative of BOTA, Chris has played a pivotal role in advancing orthopaedic research and practice.

Research

Research Interests:

Chris had led priority setting partnerships in complex fractures and major trauma as well as being a co-investigator on several randomised clinical trials in the field of orthopaedic trauma. His research focuses on clinical and cost-effectiveness studies in trauma, and he is developing an international network to answer future questions in this area. These studies will involve testing established as well as novel treatments for global orthopaedic care.

Publications

• The Open-Fracture Patient Evaluation Nationwide (OPEN) study: the management of open fracture care in the UK.
  Winstanley RJH, Hadfield JN, Walker R, Bretherton CP, Ashwood N, Allison K, Trompeter A, Eardley WGP; Open-Fracture Patient Evaluation Nationwide (OPEN) collaborators.
  Bone Jt Open. 2022 Oct;3(10):746-752. doi: 10.1302/2633-1462.310.BJO-2022-0079.R1.PMID: 36181319 
  
  
• The Fragility Fracture Postoperative Mobilisation multicentre audit: the reality of weightbearing practices following operations for lower limb fragility fractures.
  Richardson C, Bretherton CP, Raza M, Zargaran A, Eardley WGP, Trompeter AJ; FFPOM Collaborators. Bone Joint J. 2022 Aug;104-B(8):972-979. doi: 10.1302/0301-620X.104B8.BJJ-2022-0074.R1.PMID: 35909372
  
  
• Research priorities for the management of complex fractures: a UK priority setting partnership with the James Lind Alliance. Bretherton CP, Claireaux HA, Gower J, Martin S, Thornhill A, Johnson L, Silvester L, Kearney RS, Baxter M, Dixon P, Giblin V, Griffin XL, Eardley W.BMJ Open. 2021 Nov 30;11(11):e057198. doi: 10.1136/bmjopen-2021-057198.PMID: 34848529
  
  
• Protocol for the Weight-bearing in Ankle Fractures (WAX) trial: a multicentre prospective non-inferiority trial of early versus delayed weight-bearing after operatively managed ankle fracture. Bretherton CP, Claireaux HA, Achten J, Athwal A, Dutton SJ, Peckham N, Petrou S, Kearney RS, Appelbe D, Griffin XL.BMC Musculoskelet Disord. 2021 Aug 9;22(1):672. doi: 10.1186/s12891-021-04560-7. PMID: 34372803
  
  
• Weight-bearing in Trauma Surgery (WiTS) Study: A national survey of UK Trauma & Orthopaedic multidisciplinary health professionals. Raza M, Walters S, Richardson C, Bretherton C, Longhurst K, Trompeter A. Injury. 2021 Dec 12:S0020-1383(21)01006-8. doi: 10.1016/j.injury.2021.12.019. Online ahead of print. PMID: 34937671