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Professor Patrick Kennedy, MB BCh BAO BMedSci FRCP MD

Patrick

Clinical Professor of Translational Hepatology

Centre: Immunobiology

Email: p.kennedy@qmul.ac.uk
Telephone: 020 7882 2275

Profile

Professor Kennedy is a leading liver specialist and his work in viral liver disease is known internationally. Trained in University College Dublin, he completed post-graduate training in London and was appointed as a Senior Lecturer at Barts and The London School of Medicine and Dentistry in 2009. He has produced novel work redefining disease phase in Chronic Hepatitis B (CHB).

His primary research interest is in Hepatitis B virus (HBV) within a translational platform. He has a special interest in liver disease in young people, specifically HBV; he set up and runs the dedicated young adult liver service at The Royal London Hospital. He is widely published in viral liver disease and has almost 100 peer reviewed publications in addition to multiple book chapters and he has also edited a textbook of Gastrohepatology. His work in HBV is known internationally. He has produced novel work redefining disease phase and described clonal hepatocyte expansion and HBV DNA integration in young patients with HBeAg positive chronic infection (formerly referred to as “immune tolerant” patients), the foundation for the re-evaluation of treatment candidacy in Chronic Hepatitis B (CHB). He is a passionate advocate for early treatment (and broadening treatment access) in CHB to prevent disease progression and liver cancer. Developing these themes, an important focus of his current work is individualized treatment strategies for CHB, namely the early initiation of antiviral therapy and then access to novel therapies as part of the HBV functional cure program. Professor Kennedy is the chief/principal investigator for a number of investigator-led and commercial phase 1, 2 and 3, clinical trials in CHB and hepatitis delta virus (HDV). This clinical trial portfolio dovetails his longstanding research interest and publication record, the ultimate goal of which is achieving HBV cure.

Professor Kennedy is the current Chair of the British Viral Hepatitis Group (BVHG) and former lead for the British Association for the Study of the Liver (BASL) special interest group in HBV. He is a member of the WHO guideline development group and the EASL CHB clinical practice guidelines. He provides expert opinion for the United Kingdom Advisory Panel on blood-borne viruses, in addition he is a key opinion leader in viral liver disease and a member of expert advisory panels for early drug development.

Summary

Professor Patrick Kennedy is a Clinical Professor of Translational Hepatology at the Faculty of Medicine and Dentistry (FMD), QMUL and Consultant Hepatologist at Barts Health NHS Trust.

His research focuses in translational aspects of Hepatitis B virus. He is also leads the Hepatitis B clinical service and runs the young adult Hepatology service at The Royal London Hospital.

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