Dr Patrick Pallier, PhD, FHEA

Profile

Patrick Pallier did his PhD at INSERM in Bordeaux, France. He then worked as a post-doctoral researcher in the School of Psychology at the University of St Andrews, Scotland, and in the Department of Pharmacology at Cambridge University, before joining Prof. Adina Michael-Titus and Prof. John Priestley at Queen Mary University of London, in the Centre for Neuroscience, Surgery and Trauma in the Blizard Institute, where he became a Lecturer and then Senior Lecturer in Neuroscience. He is a member of the QMUL Centre for Predictive in vitro Models (https://www.cpm.qmul.ac.uk/) but his research also uses a wide array of in vivo techniques. He is a Fellow of The Higher Education Academy.

Teaching

Undergraduate and Post-graduate taught courses:

• MBBS: Brain and Behaviour module: (module co-lead Year 1, lecturer, tutor for Problem-Based Learning, Year 1 and 2)
• Medicine Graduate Entry Programme: Brain and Behaviour module (module co-lead and lecturer)
• Intercalated BSc Neuroscience: Disconnected Pathways module and Brain and Mind module (lecturer)
• BSc (Hon) Neuroscience: Perspectives on Brain Disorders module (lecturer); Systems Neuroscience (lecturer)
• MSc Neuroscience and Translational Medicine: Chronic pain and epilepsy (module co-lead and lecturer); Neuro-oncology (module co-lead); Research projects (module co-lead)

Laboratory-based and Non-laboratory-based project Supervisor: BSc (Hon) Neuroscience; BSc in Biomedical Sciences; MSc Neuroscience and Translational Medicine; MSc in Regenerative Medicine; SSC

Academic advisor for BSc (Hon) Neuroscience (Year 1 to 3) and MSc Neuroscience and Translational Medicine students

Research

Research Interests:

Dr Patrick Pallier's current research focuses on neuroprotection and repair after trauma (brain, spinal cord), and in ageing and neurodegenerative conditions.

Recent and ongoing research projects:

· Development of specialised nutritional interventions in neurotrauma and hypoxic-ischemic en-cephalopathy

· Development of fatty acid emulsions for use in acute neuroprotection in spinal cord injury

· Development of new compounds with neuroprotective and neurotrophic properties

· Protecting the brain vasculature after trauma

· White matter ageing

Group members:

· Tatenda Mutshiya (Research technician)

Publications

Key Publications

Thau-Zuchman O, Ingram R, Harvey GG, Cooke T, Palmas F, Pallier PN, Brook J, Priestley JV, Dalli J, Tremoleda JL, Michael-Titus AT (2019) A Single Injection of Docosahexaenoic Acid Induces a Pro-Resolving Lipid Mediator Profile in the Injured Tissue and a Long-Lasting Reduction in Neurological Deficit after Traumatic Brain Injury in Mice. Journal of Neurotrauma vol. 37, (1) 66-79. doi: 10.1089/neu.2019.6420.

Gushchina S, Pryce G, Yip PK, Wu D, Pallier PN, Giovannoni G, Baker D and Bo X (2018) Increased expression of colony-stimulating factor-1 in mouse spinal cord with experimental autoimmune encephalomyelitis correlates with microglial activation and neuronal loss. Glia vol. 66, (10) 2108-2125. doi: 10.1002/glia.23464.

Pallier PN, Poddighe L, Zbarsky V, Kostusiak M, Choudhury R, Hart T, Burguillos MA, Musbahi O, Groenendijk M, Sijben JW, deWilde MC, Quartu M, Priestley JV and Michael-Titus AT (2015) A nutrient combination designed to enhance synapse formation and function improves outcome in experimental spinal cord injury. Neurobiology of Disease vol. 82, 504-515.

Ward RE, Huang W, Kostusiak M, Pallier PN, Michael-Titus AT and Priestley JV (2014) A characterization of white matter pathology following spinal cord compression injury in the rat. Neuroscience vol. 260, 227-239.

All Publications

Supervision

• Mehmet Eren Ermis (PhD student)