Platelets and platelet-derived microvesicles as novel modifiers of innate immunity and inflammation

Platelets, in addition to maintaining haemostasis, are increasingly appreciated as contributing to immunological and inflammatory diseases including cancer, diabetes and sepsis. We are only beginning to understand the mechanisms and functions of the complex interplay between platelets and immune cells. This project will address the hypothesis that platelets and their derived microvesicles play a key role in modifying inflammation and immune function through their interaction and influence on leukocytes and T-cells. Moreover, as platelets are proven targets for daily prophylactic therapies, this makes them an attractive target for future therapeutics aimed at chronic disease.

Applications are invited from candidates with at least an upper-second class honours degree or equivalent in an area relevant to the project. Proficient English language skills are essential. Please contact Professor Tim Warner (t.d.warner@qmul.ac.uk) to apply.