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Dr Harriet Larvin

Harriet

Research Fellow in Health Data Science

Email: h.larvin@qmul.ac.uk

Profile

I hold the position of Research Fellow in Health Data Science within the Clinical Effectiveness Group (CEG) at the Centre for Primary Care. I work in the Precision Health Programme where I conduct in-depth analyses of electronic health records, in particular CPRD,  to explore multimorbidity, oral health and cardiovascular disease associations. My research focus involves combining statistical methods with innovative data science to chart disease trajectories, reveal multimorbidity clusters, and explore health inequalities.

I have extensively worked with various routine data sources and real-world evidence, including CPRD, HES, UK Biobank, and NHANES . Before joining QMUL, I gained valuable industry experience as a Health Data Scientist for a data-intelligence company. I previously achieved an award for Research Excellence for my PhD at the University of Leeds, where I employed a combination of statistical methods and innovative data science techniques, such as process mining and hypergraphs, to unveil intricate patterns within periodontal disease and multimorbidity. Prior to that, I completed a Master of Public Health (MPH) from the University of York where my master's dissertation investigated the case-finding accuracy of anxiety and depression within routinely collected health records.

Research

Research Interests:

  • Data science methodologies
  • Oral Health
  • Multimorbidity
  • Cardiovascular disease
  • Health inequalities

Publications

  1. *Larvin, H., Gao, C., Kang, J., Aggarwal, V.R., Pavitt, S., Wu, J. The impact of study factors in the association of periodontal disease and cognitive disorders: systematic review and meta-analysis. Age and Aging. 2023. https://doi.org/10.1093/ageing/afad015
  2. *Larvin, H., Kang, J., Aggarwal, V.R., Pavitt, S., Wu, J. Periodontitis and risk of immune‐mediated systemic conditions: A systematic review and meta‐analysis. Community Dentistry and Oral Epidemiology. 2022. https://doi.org/10.1111/cdoe.12812
  3. Kang, J., Palmier-Claus, J., Wu, J., Shiers, D., Larvin, H., Doran, T., Aggarwal, V.R. Periodontal disease in people with a history of psychosis: Results from the UK biobank population-based study. Community Dentistry and Oral Epidemiology. 2022. https://doi.org/10.1111/cdoe.12798
  4. *Larvin, H., Kang, J., Aggarwal, V.R., Pavitt, S., Wu, J. Systemic multimorbidity clusters in people with periodontitis. Journal of Dental Research. 2022. https://doi.org/10.1177/00220345221098910 
  5. *Larvin, H., Kang, J., Aggarwal, V.R., Pavitt, S., Wu, J. The additive effect of periodontitis with hypertension on risk of systemic disease and mortality. J Periodontol. 2022. https://doi.org/10.1002/JPER.21-0621
  6. *Larvin, H., Kang, J., Aggarwal, V.R., Pavitt, S. and Wu, J. Multimorbid disease trajectories for people with periodontitis. J Clin Periodontol. 2021. https://doi.org/10.1111/jcpe.13536
  7. *Larvin H, Wilmott S, Kang J, Aggarwal V. R., Pavitt S., Wu J. Additive effect of periodontal disease and obesity on COVID-19 outcomes. Journal of Dental Research. 2021. https://doi.org/10.1177/00220345211029638 
  8. *Larvin H, Wilmott S, Wu J, Kang J. The Impact of Periodontal Disease on Hospital Admission and Mortality During COVID-19 Pandemic. Frontiers in Medicine. 2020;7:861. https://doi.org/10.3389/fmed.2020.604980
  9. *Larvin H, Kang J, Aggarwal VR, Pavitt S, Wu J. Risk of incident cardiovascular disease in people with periodontal disease: A systematic review and meta-analysis. Clin Exp Dent Res. 2020. https://doi.org/10.1002/cre2.336
  10. *Larvin, H., Peckham, E., Prady, S. Case-finding for common mental health disorders in primary care using routinely collected dataː a systematic review. Journal of Social Psychiatry and Psychiatric Epidemiology. 2019. https://doi.org/10.1007/s00127-019-01744-4
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