High-Performance Computing (HPC) provides researchers with the ability to expand their data processing, simulation and computation across hundreds of cores. This has led to widespread use across many disciplines.ITS Research support, and provide access to Apocrita is a heterogeneous HPC cluster comprising around 350 nodes and 12,500 compute cores, located in the Jisc Shared data centre in Slough. The cluster has many applications installed ready for you to use; core applications (including Stata, Gaussian and MATLAB); programming languages (e.g. C, C++, Fortran, R, Python); and domain-specific research applications (e.g. for bioinformatics and computational chemistry).