Professor Claudia LangenbergDirectorEmail: claudia.langenberg@qmul.ac.ukProfilePublicationsProfileClaudia is the Director of PHURI and the former programme Leader at the MRC Epidemiology Unit at the University of Cambridge. Claudia is a public health specialist combining her expertise with research focused on molecular epidemiology. Her work integrates large-scale genomic and metabolomic data to discover, prioritise and characterize metabolic pathways and test their causal relevance and specificity across a range of diseases, uncovering genetic influences on thousands of molecules in the blood, using this knowledge to better understand human disease such as type 2 diabetes. In 2018 Claudia received the Helmholtz International Fellow Award and was named in the top 20 female scientists in the UK in 2022.ResearchPublications Jacobs BM, Stow D, Hodgson S et al. (publicationYear). Genetic architecture of routinely acquired blood tests in a British South Asian cohort. nameOfConference DOI: 10.1038/s41467-024-53091-x QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/100687 Gordillo-Marañón M, Schmidt AF, Warwick A et al. (publicationYear). Disease coverage of human genome-wide association studies and pharmaceutical research and development. nameOfConference DOI: 10.1038/s43856-024-00625-5 QMRO: qmroHref Carrasco-Zanini J, Wheeler E, Uluvar B et al. (2024). Mapping biological influences on the human plasma proteome beyond the genome. nameOfConference DOI: 10.1038/s42255-024-01133-5 QMRO: qmroHref Lockhart SM, Muso M, Zvetkova I et al. (2024). Damaging mutations in liver X receptor-α are hepatotoxic and implicate cholesterol sensing in liver health. nameOfConference DOI: 10.1038/s42255-024-01126-4 QMRO: qmroHref Repetto L, Chen J, Yang Z et al. (2024). The genetic landscape of neuro-related proteins in human plasma. nameOfConference DOI: 10.1038/s41562-024-01963-z QMRO: qmroHref Alwan H, Luan J, Williamson A et al. (2024). Testing for a causal role of thyroid hormone measurements within the normal range on human metabolism and diseases: a systematic Mendelian randomization. nameOfConference DOI: 10.1016/j.ebiom.2024.105306 QMRO: qmroHref Chen Y, Butler-Laporte G, Liang KYH et al. (2024). The performance of AlphaMissense to identify genes influencing disease. nameOfConference DOI: 10.1016/j.xhgg.2024.100344 QMRO: qmroHref Gomez EA, De Matteis R, Udomjarumanee P et al. (2024). An LGR6 frameshift variant abrogates receptor expression on select leukocyte subsets and is associated with viral infections. nameOfConference DOI: 10.1182/blood.2023021826 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/98892 (2024). Blood proteins predict the risk of many diseases years before onset. nameOfConference DOI: 10.1038/s41591-024-03145-w QMRO: qmroHref Carrasco-Zanini J, Pietzner M, Davitte J et al. (2024). Proteomic signatures improve risk prediction for common and rare diseases. nameOfConference DOI: 10.1038/s41591-024-03142-z QMRO: qmroHref Lim SS, Semnani-Azad Z, Morieri ML et al. (2024). Reporting guidelines for precision medicine research of clinical relevance: the BePRECISE checklist. nameOfConference DOI: 10.1038/s41591-024-03033-3 QMRO: qmroHref Pietzner M, Denaxas S, Yasmeen S et al. (publicationYear). Complex patterns of multimorbidity associated with severe COVID-19 and long COVID. nameOfConference DOI: 10.1038/s43856-024-00506-x QMRO: qmroHref Carrasco-Zanini J, Pietzner M, Koprulu M et al. (2024). Proteomic prediction of diverse incident diseases: a machine learning-guided biomarker discovery study using data from a prospective cohort study. nameOfConference DOI: 10.1016/s2589-7500(24)00087-6 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/98189 Stefanucci L, Moslemi C, Tomé AR et al. (2024). SMIM1 absence is associated with reduced energy expenditure and excess weight. nameOfConference DOI: 10.1016/j.medj.2024.05.015 QMRO: qmroHref Desai TA, Hedman ÅK, Dimitriou M et al. (2024). Identifying proteomic risk factors for overall, aggressive, and early onset prostate cancer using Mendelian Randomisation and tumour spatial transcriptomics. nameOfConference DOI: 10.1016/j.ebiom.2024.105168 QMRO: qmroHref Steinfeldt J, Wild B, Buergel T et al. (publicationYear). RETRACTED ARTICLE: Medical history predicts phenome-wide disease onset and enables the rapid response to emerging health threats. nameOfConference DOI: 10.1038/s41467-024-48568-8 QMRO: qmroHref Keaton JM, Kamali Z, Xie T et al. (2024). Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits. nameOfConference DOI: 10.1038/s41588-024-01714-w QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/99886 Smith-Byrne K, Hedman Å, Dimitriou M et al. (publicationYear). Identifying therapeutic targets for cancer among 2074 circulating proteins and risk of nine cancers. nameOfConference DOI: 10.1038/s41467-024-46834-3 QMRO: qmroHref Shrine N, Guyatt AL, Erzurumluoglu AM et al. (2024). Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. nameOfConference DOI: 10.1038/s41588-024-01752-4 QMRO: qmroHref Liew F, Efstathiou C, Fontanella S et al. (2024). Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease. nameOfConference DOI: 10.1038/s41590-024-01778-0 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/98487 Elneima O, Hurst JR, Echevarria C et al. (2024). Long-term impact of COVID-19 hospitalisation among individuals with pre-existing airway diseases in the UK: a multicentre, longitudinal cohort study – PHOSP-COVID. nameOfConference DOI: 10.1183/23120541.00982-2023 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/98486 Desai TA, Hedman AK, Dimitriou M et al. (2024). Abstract 7330: Identifying proteomic risk factors for overall, aggressive and early onset prostate cancer using mendelian randomization and tumor spatial transcriptomics. nameOfConference DOI: 10.1158/1538-7445.am2024-7330 QMRO: qmroHref Ganji-Arjenaki M, Kamali Z, Pressure ICOB et al. (2024). Prioritization of Kidney Cell Types Highlights Myofibroblast Cells in Regulating Human Blood Pressure. nameOfConference DOI: 10.1016/j.ekir.2024.03.001 QMRO: qmroHref Pietzner M, Uluvar B, Kolnes KJ et al. (2024). Systemic proteome adaptions to 7-day complete caloric restriction in humans. nameOfConference DOI: 10.1038/s42255-024-01008-9 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/95123 (2024). Genetic drivers of heterogeneity in type 2 diabetes pathophysiology. nameOfConference DOI: 10.1038/s41586-024-07019-6 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/95027 Sterenborg RBTM, Steinbrenner I, Li Y et al. (publicationYear). Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications. nameOfConference DOI: 10.1038/s41467-024-44701-9 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/95973 Lord JM, Veenith T, Sullivan J et al. (publicationYear). Accelerated immune ageing is associated with COVID-19 disease severity. nameOfConference DOI: 10.1186/s12979-023-00406-z QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/95464 Noce D, Foco L, Orth-Höller D et al. (2024). Genetic determinants of complement activation in the general population. nameOfConference DOI: 10.1016/j.celrep.2023.113611 QMRO: qmroHref Elneima O, McAuley HJC, Leavy OC et al. (2024). Cohort Profile: Post-Hospitalisation COVID-19 (PHOSP-COVID) study. nameOfConference DOI: 10.1093/ije/dyad165 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/94010 Trichia E, Koulman A, Stewart ID et al. (2024). Plasma Metabolites Related to the Consumption of Different Types of Dairy Products and Their Association with New‐Onset Type 2 Diabetes: Analyses in the Fenland and EPIC‐Norfolk Studies, United Kingdom. nameOfConference DOI: 10.1002/mnfr.202300154 QMRO: qmroHref Collaboration ERFCE-CVDS, Sofianopoulou E, Kaptoge SK et al. (2024). Estimating dose-response relationships for vitamin D with coronary heart disease, stroke, and all-cause mortality: observational and Mendelian randomisation analyses. nameOfConference DOI: 10.1016/s2213-8587(23)00287-5 QMRO: qmroHref Iglesias MJ, Sanchez-Rivera L, Ibrahim-Kosta M et al. (publicationYear). Author Correction: Elevated plasma complement factor H related 5 protein is associated with venous thromboembolism. nameOfConference DOI: 10.1038/s41467-023-43764-4 QMRO: qmroHref Tin A, Fohner AE, Yang Q et al. (publicationYear). Identification of circulating proteins associated with general cognitive function among middle-aged and older adults. nameOfConference DOI: 10.1038/s42003-023-05454-1 QMRO: qmroHref Yoshiji S, Lu T, Butler-Laporte G et al. (2023). INTEGRATIVE PROTEOGENOMICS ANALYSIS IDENTIFIES COL6A3-DERIVED ENDOTROPHIN AS AN ACTIONABLE MEDIATOR OF THE EFFECT OF OBESITY ON CORONARY ARTERY DISEASE. nameOfConference DOI: 10.1016/j.jcjd.2023.10.324 QMRO: qmroHref Carrasco-Zanini J, Pietzner M, Wheeler E et al. (2024). Multi-omic prediction of incident type 2 diabetes. nameOfConference DOI: 10.1007/s00125-023-06027-x QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/93682 Willems SM, Ng NHJ, Fernandez J et al. (publicationYear). Large-scale exome array summary statistics resources for glycemic traits to aid effector gene prioritization. nameOfConference DOI: 10.12688/wellcomeopenres.18754.1 QMRO: qmroHref Willems SM, Ng NHJ, Fernandez J et al. (2023). Large-scale exome array summary statistics resources for glycemic traits to aid effector gene prioritization.. nameOfConference DOI: 10.12688/wellcomeopenres.18754.1 QMRO: qmroHref Hingorani AD, Gratton J, Finan C et al. (2023). Performance of polygenic risk scores in screening, prediction, and risk stratification: secondary analysis of data in the Polygenic Score Catalog. nameOfConference DOI: 10.1136/bmjmed-2023-000554 QMRO: qmroHref Brightling CE, Evans RA, Singapuri A et al. (2023). Long COVID research: an update from the PHOSP-COVID Scientific Summit. nameOfConference DOI: 10.1016/s2213-2600(23)00341-7 QMRO: qmroHref Hartmann S, Yasmeen S, Jacobs BM et al. (publicationYear). ADRA2A and IRX1 are putative risk genes for Raynaud’s phenomenon. nameOfConference DOI: 10.1038/s41467-023-41876-5 QMRO: qmroHref Yoshiji S, Lu T, Butler-Laporte G et al. (2023). THU582 Actionable Circulating Proteins Mediate The Effect Of Obesity On Cardiometabolic Diseases: An Integrative Proteogenomics Analysis. nameOfConference DOI: 10.1210/jendso/bvad114.580 QMRO: qmroHref Yoshiji S, Lu T, Butler-Laporte G et al. (2023). INTEGRATIVE PROTEOGENOMICS ANALYSIS IDENTIFIES COL6A3-DERIVED ENDOTROPHIN AS AN ACTIONABLE MEDIATOR OF THE EFFECT OF OBESITY ON CORONARY ARTERY DISEASE. nameOfConference DOI: 10.1016/j.cjca.2023.06.321 QMRO: qmroHref Fethnou E, Qafoud F, Alkhayat E et al. (2023). Author Correction: Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk. nameOfConference DOI: 10.1038/s41588-023-01531-7 QMRO: qmroHref Brightling CE, Evans RA, Wain LV et al. (2023). Multiorgan MRI findings after hospitalisation with COVID-19 in the UK (C-MORE): a prospective, multicentre, observational cohort study. nameOfConference DOI: 10.1016/s2213-2600(23)00262-x QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/98488 Lagou V, Jiang L, Ulrich A et al. (2023). GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification. nameOfConference DOI: 10.1038/s41588-023-01462-3 QMRO: qmroHref Noce D, Foco L, Orth-Höller D et al. (2023). 176 A genome-wide association screening of complement activation from a general population study. nameOfConference DOI: 10.1016/j.imbio.2023.152626 QMRO: qmroHref Alwan H, Luan J, Williamson A et al. (publicationYear). Testing for a causal role of thyroid hormone measurements within the normal range: a systematic mendelian randomization study. nameOfConference DOI: 10.1530/endoabs.92.op-08-04 QMRO: qmroHref Zhou S, Sosina OA, Bovijn J et al. (2023). Converging evidence from exome sequencing and common variants implicates target genes for osteoporosis. nameOfConference DOI: 10.1038/s41588-023-01444-5 QMRO: qmroHref Carland C, Png G, Malarstig A et al. (2023). Proteomic analysis of 92 circulating proteins and their effects in cardiometabolic diseases. nameOfConference DOI: 10.1186/s12014-023-09421-0 QMRO: qmroHref Zheng J, Wheeler E, Pietzner M et al. (2023). Lowering of Circulating Sclerostin May Increase Risk of Atherosclerosis and Its Risk Factors: Evidence From a Genome‐Wide Association Meta‐Analysis Followed by Mendelian Randomization. nameOfConference DOI: 10.1002/art.42538 QMRO: qmroHref van der Spek A, Stewart ID, Kühnel B et al. (2023). Circulating metabolites modulated by diet are associated with depression. nameOfConference DOI: 10.1038/s41380-023-02180-2 QMRO: qmroHref Langenberg C, Hingorani AD, Whitty CJM (2023). Biological and functional multimorbidity—from mechanisms to management. nameOfConference DOI: 10.1038/s41591-023-02420-6 QMRO: qmroHref Rasooly D, Peloso GM, Pereira AC et al. (publicationYear). Genome-wide association analysis and Mendelian randomization proteomics identify drug targets for heart failure. nameOfConference DOI: 10.1038/s41467-023-39253-3 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/89555 Cai L, Gonzales T, Wheeler E et al. (publicationYear). Causal associations between cardiorespiratory fitness and type 2 diabetes. nameOfConference DOI: 10.1038/s41467-023-38234-w QMRO: qmroHref Williamson A, Norris DM, Yin X et al. (2023). Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake. nameOfConference DOI: 10.1038/s41588-023-01408-9 QMRO: qmroHref Iglesias MJ, Sanchez-Rivera L, Ibrahim-Kosta M et al. (publicationYear). Elevated plasma complement factor H related 5 protein is associated with venous thromboembolism. nameOfConference DOI: 10.1038/s41467-023-38383-y QMRO: qmroHref Graham SE, Clarke SL, Wu K-HH et al. (2023). Author Correction: The power of genetic diversity in genome-wide association studies of lipids. nameOfConference DOI: 10.1038/s41586-023-06194-2 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/92162 Li JH, Brenner LN, Kaur V et al. (2023). Genome-wide association analysis identifies ancestry-specific genetic variation associated with acute response to metformin and glipizide in SUGAR-MGH. nameOfConference DOI: 10.1007/s00125-023-05922-7 QMRO: qmroHref Zheng B, Vivaldi G, Daines L et al. (2023). Determinants of recovery from post-COVID-19 dyspnoea: analysis of UK prospective cohorts of hospitalised COVID-19 patients and community-based controls. nameOfConference DOI: 10.1016/j.lanepe.2023.100635 QMRO: qmroHref Su C-Y, Zhou S, Gonzalez-Kozlova E et al. (publicationYear). Circulating proteins to predict COVID-19 severity. nameOfConference DOI: 10.1038/s41598-023-31850-y QMRO: qmroHref Jackson C, Stewart ID, Plekhanova T et al. (2023). Effects of sleep disturbance on dyspnoea and impaired lung function following hospital admission due to COVID-19 in the UK: a prospective multicentre cohort study. nameOfConference DOI: 10.1016/s2213-2600(23)00124-8 QMRO: qmroHref Xu Y, Ritchie SC, Liang Y et al. (2023). An atlas of genetic scores to predict multi-omic traits. nameOfConference DOI: 10.1038/s41586-023-05844-9 QMRO: qmroHref Koprulu M, Carrasco-Zanini J, Wheeler E et al. (2023). Author Correction: Proteogenomic links to human metabolic diseases. nameOfConference DOI: 10.1038/s42255-023-00785-z QMRO: qmroHref Fethnou E, Qafoud F, Alkhayat E et al. (2023). Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk. nameOfConference DOI: 10.1038/s41588-023-01314-0 QMRO: qmroHref McAuley HJC, Evans RA, Bolton CE et al. (2023). Prevalence of physical frailty, including risk factors, up to 1 year after hospitalisation for COVID-19 in the UK: a multicentre, longitudinal cohort study. nameOfConference DOI: 10.1016/j.eclinm.2023.101896 QMRO: qmroHref Mathieson I, Day FR, Barban N et al. (2023). Genome-wide analysis identifies genetic effects on reproductive success and ongoing natural selection at the FADS locus. nameOfConference DOI: 10.1038/s41562-023-01528-6 QMRO: qmroHref Koprulu M, Carrasco-Zanini J, Wheeler E et al. (2023). Proteogenomic links to human metabolic diseases. nameOfConference DOI: 10.1038/s42255-023-00753-7 QMRO: qmroHref Xu F, Yu EY-W, Cai X et al. (publicationYear). Genome-wide genotype-serum proteome mapping provides insights into the cross-ancestry differences in cardiometabolic disease susceptibility. nameOfConference DOI: 10.1038/s41467-023-36491-3 QMRO: qmroHref Repetto L, Chen J, Yang Z et al. (publicationYear). Genetic mechanisms of 184 neuro-related proteins in human plasma. nameOfConference DOI: 10.1101/2023.02.10.23285650 QMRO: qmroHref Strain T, Dempsey PC, Wijndaele K et al. (2023). Quantifying the Relationship Between Physical Activity Energy Expenditure and Incident Type 2 Diabetes: A Prospective Cohort Study of Device-Measured Activity in 90,096 Adults. nameOfConference DOI: 10.2337/dc22-1467 QMRO: qmroHref Zhao J, Stewart ID, Baird D et al. (2023). Causal effects of maternal circulating amino acids on offspring birthweight: a Mendelian randomisation study. nameOfConference DOI: 10.1016/j.ebiom.2023.104441 QMRO: qmroHref Broadaway KA, Yin X, Williamson A et al. (2023). Loci for insulin processing and secretion provide insight into type 2 diabetes risk. nameOfConference DOI: 10.1016/j.ajhg.2023.01.002 QMRO: qmroHref Vernardis SI, Demichev V, Lemke O et al. (2023). The Impact of Acute Nutritional Interventions on the Plasma Proteome. nameOfConference DOI: 10.1210/clinem/dgad031 QMRO: qmroHref Bakker MK, Kanning JP, Abraham G et al. (2023). Genetic Risk Score for Intracranial Aneurysms: Prediction of Subarachnoid Hemorrhage and Role in Clinical Heterogeneity. nameOfConference DOI: 10.1161/strokeaha.122.040715 QMRO: qmroHref Kentistou KA, Luan J, Wittemans LBL et al. (publicationYear). Large scale phenotype imputation and in vivo functional validation implicate ADAMTS14 as an adiposity gene. nameOfConference DOI: 10.1038/s41467-022-35563-0 QMRO: qmroHref Chen Y, Lu T, Pettersson-Kymmer U et al. (2023). Genomic atlas of the plasma metabolome prioritizes metabolites implicated in human diseases. nameOfConference DOI: 10.1038/s41588-022-01270-1 QMRO: qmroHref Kanoni S, Graham SE, Wang Y et al. (publicationYear). Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis. nameOfConference DOI: 10.1186/s13059-022-02837-1 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/84269 Liew F, Talwar S, Cross A et al. (2023). SARS-CoV-2-specific nasal IgA wanes 9 months after hospitalisation with COVID-19 and is not induced by subsequent vaccination. nameOfConference DOI: 10.1016/j.ebiom.2022.104402 QMRO: qmroHref Gardner EJ, Kentistou KA, Stankovic S et al. (2022). Damaging missense variants in IGF1R implicate a role for IGF-1 resistance in the etiology of type 2 diabetes. nameOfConference DOI: 10.1016/j.xgen.2022.100208 QMRO: qmroHref Kuan V, Denaxas S, Patalay P et al. (2023). Identifying and visualising multimorbidity and comorbidity patterns in patients in the English National Health Service: a population-based study. nameOfConference DOI: 10.1016/s2589-7500(22)00187-x QMRO: qmroHref Butler-Laporte G, Gonzalez-Kozlova E, Su C-Y et al. (2022). Correction: The dynamic changes and sex differences of 147 immune-related proteins during acute COVID-19 in 580 individuals. nameOfConference DOI: 10.1186/s12014-022-09378-6 QMRO: qmroHref de Laat KF, van Norden AGW, de Kort PL et al. (2022). Publisher Correction: Stroke genetics informs drug discovery and risk prediction across ancestries. nameOfConference DOI: 10.1038/s41586-022-05492-5 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/98489 (2022). Broad-capture proteomics and machine learning for early detection of type 2 diabetes risk. nameOfConference DOI: 10.1038/s41591-022-02056-y QMRO: qmroHref Carrasco-Zanini J, Pietzner M, Lindbohm JV et al. (2022). Proteomic signatures for identification of impaired glucose tolerance. nameOfConference DOI: 10.1038/s41591-022-02055-z QMRO: qmroHref Surendran P, Stewart ID, Au Yeung VPW et al. (2022). Rare and common genetic determinants of metabolic individuality and their effects on human health. nameOfConference DOI: 10.1038/s41591-022-02046-0 QMRO: qmroHref Gaziano L, Sun L, Arnold M et al. (2022). Mild-to-Moderate Kidney Dysfunction and Cardiovascular Disease: Observational and Mendelian Randomization Analyses. nameOfConference DOI: 10.1161/circulationaha.122.060700 QMRO: qmroHref Yengo L, Vedantam S, Marouli E et al. (2022). A saturated map of common genetic variants associated with human height. nameOfConference DOI: 10.1038/s41586-022-05275-y QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/84268 de Laat KF, van Norden AGW, de Kort PL et al. (2022). Stroke genetics informs drug discovery and risk prediction across ancestries. nameOfConference DOI: 10.1038/s41586-022-05165-3 QMRO: qmroHref Butler-Laporte G, Gonzalez-Kozlova E, Su C-Y et al. (2022). The dynamic changes and sex differences of 147 immune-related proteins during acute COVID-19 in 580 individuals. nameOfConference DOI: 10.1186/s12014-022-09371-z QMRO: qmroHref Buergel T, Steinfeldt J, Ruyoga G et al. (2022). Metabolomic profiles predict individual multidisease outcomes. nameOfConference DOI: 10.1038/s41591-022-01980-3 QMRO: qmroHref P K, ID S, RS K et al. (publicationYear). Metabolomic profiling reveals extensive adrenal suppression due to inhaled corticosteroid therapy in asthma. nameOfConference DOI: 10.1530/ey.19.15.10 QMRO: qmroHref Wang Z, Emmerich A, Pillon NJ et al. (2022). Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention. nameOfConference DOI: 10.1038/s41588-022-01165-1 QMRO: qmroHref Pietzner M, Chua RL, Wheeler E et al. (publicationYear). ELF5 is a potential respiratory epithelial cell-specific risk gene for severe COVID-19. nameOfConference DOI: 10.1038/s41467-022-31999-6 QMRO: qmroHref Ramdas S, Judd J, Graham SE et al. (2022). A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids. nameOfConference DOI: 10.1016/j.ajhg.2022.06.012 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/84264 Kuo F-C, Neville MJ, Sabaratnam R et al. (2022). HOTAIR interacts with PRC2 complex regulating the regional preadipocyte transcriptome and human fat distribution. nameOfConference DOI: 10.1016/j.celrep.2022.111136 QMRO: qmroHref Taylor K, McBride N, Zhao J et al. (publicationYear). The Relationship of Maternal Gestational Mass Spectrometry-Derived Metabolites with Offspring Congenital Heart Disease: Results from Multivariable and Mendelian Randomization Analyses. nameOfConference DOI: 10.3390/jcdd9080237 QMRO: qmroHref Kachroo P, Stewart ID, Kelly RS et al. (2022). Author Correction: Metabolomic profiling reveals extensive adrenal suppression due to inhaled corticosteroid therapy in asthma. nameOfConference DOI: 10.1038/s41591-022-01949-2 QMRO: qmroHref Li C, Imamura F, Wedekind R et al. (2022). Development and validation of a metabolite score for red meat intake: an observational cohort study and randomized controlled dietary intervention. nameOfConference DOI: 10.1093/ajcn/nqac094 QMRO: qmroHref Zhao Y, Gardner EJ, Tuke MA et al. (2022). Detection and characterization of male sex chromosome abnormalities in the UK Biobank study. nameOfConference DOI: 10.1016/j.gim.2022.05.011 QMRO: qmroHref Li Y, Cheng Y, Consolato F et al. (2022). Genome-wide studies reveal factors associated with circulating uromodulin and its relations with complex diseases. nameOfConference DOI: 10.1172/jci.insight.157035 QMRO: qmroHref Bomba L, Walter K, Guo Q et al. (2022). Whole-exome sequencing identifies rare genetic variants associated with human plasma metabolites. nameOfConference DOI: 10.1016/j.ajhg.2022.04.009 QMRO: qmroHref Mahajan A, Spracklen CN, Zhang W et al. (2022). Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation. nameOfConference DOI: 10.1038/s41588-022-01058-3 QMRO: qmroHref Guyatt A, John C, Williams AT et al. (2023). Mendelian randomisation of eosinophils and other cell types in relation to lung function and disease. nameOfConference DOI: 10.1136/thoraxjnl-2021-217993 QMRO: qmroHref LI Y, Cheng Y, Consolato F et al. (2022). MO048: Genome-wide studies reveal factors associated with circulating uromodulin and its relations with complex diseases. nameOfConference DOI: 10.1093/ndt/gfac062.029 QMRO: qmroHref Evans RA, Leavy OC, Richardson M et al. (2022). Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study. nameOfConference DOI: 10.1016/s2213-2600(22)00127-8 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/81018 Fortuin-de Smidt MC, Sewe MO, Lassale C et al. (2022). Physical activity attenuates but does not eliminate coronary heart disease risk amongst adults with risk factors: EPIC-CVD case-cohort study. nameOfConference DOI: 10.1093/eurjpc/zwac055 QMRO: qmroHref Yang Z, Macdonald-Dunlop E, Chen J et al. (2022). Genetic Landscape of the ACE2 Coronavirus Receptor. nameOfConference DOI: 10.1161/circulationaha.121.057888 QMRO: qmroHref Temprano‐Sagrera G, Sitlani CM, Bone WP et al. (2022). Multi‐phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations. nameOfConference DOI: 10.1111/jth.15698 QMRO: qmroHref Kachroo P, Stewart ID, Kelly RS et al. (2022). Metabolomic profiling reveals extensive adrenal suppression due to inhaled corticosteroid therapy in asthma. nameOfConference DOI: 10.1038/s41591-022-01714-5 QMRO: qmroHref Dam V, Onland-Moret NC, Burgess S et al. (2022). Genetically Determined Reproductive Aging and Coronary Heart Disease: A Bidirectional 2-sample Mendelian Randomization. nameOfConference DOI: 10.1210/clinem/dgac171 QMRO: qmroHref Seyres D, Cabassi A, Lambourne JJ et al. (2022). Transcriptional, epigenetic and metabolic signatures in cardiometabolic syndrome defined by extreme phenotypes. nameOfConference DOI: 10.1186/s13148-022-01257-z QMRO: qmroHref John C, Guyatt AL, Shrine N et al. (2022). Genetic Associations and Architecture of Asthma-COPD Overlap. nameOfConference DOI: 10.1016/j.chest.2021.12.674 QMRO: qmroHref Taylor-Bateman V, Gill D, Georgakis MK et al. (2022). Cardiovascular Risk Factors and MRI Markers of Cerebral Small Vessel Disease. nameOfConference DOI: 10.1212/wnl.0000000000013120 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/75770 Murphy N, Song M, Papadimitriou N et al. (2022). Associations Between Glycemic Traits and Colorectal Cancer: A Mendelian Randomization Analysis. nameOfConference DOI: 10.1093/jnci/djac011 QMRO: qmroHref Perry BI, Bowker N, Burgess S et al. (2022). Evidence for Shared Genetic Aetiology Between Schizophrenia, Cardiometabolic, and Inflammation-Related Traits: Genetic Correlation and Colocalization Analyses. nameOfConference DOI: 10.1093/schizbullopen/sgac001 QMRO: qmroHref Li Y, Cheng Y, Consolato F et al. (2022). GENOME-WIDE STUDIES REVEAL FACTORS ASSOCIATED WITH CIRCULATING UROMODULIN AND ITS RELATIONS WITH COMPLEX DISEASES. nameOfConference DOI: doi QMRO: qmroHref Warren H, Keaton J, Kamali Z et al. (2022). Genome-wide analysis in over 1 million individuals reveals over 2,000 independent genetic signals for blood pressure. nameOfConference DOI: doi QMRO: qmroHref Koprulu M, Carrasco-Zanini J, Wheeler E et al. (2022). Understanding Disease Mechanisms: From Genome to Phenome via the Proteome. nameOfConference DOI: doi QMRO: qmroHref Graham SE, Clarke SL, Wu K-HH et al. (2021). The power of genetic diversity in genome-wide association studies of lipids. nameOfConference DOI: 10.1038/s41586-021-04064-3 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/75769 Koprulu M, Zhao Y, Wheeler E et al. (2022). Identification of Rare Loss-of-Function Genetic Variation Regulating Body Fat Distribution. nameOfConference DOI: 10.1210/clinem/dgab877 QMRO: qmroHref Png G, Barysenka A, Repetto L et al. 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Estimating dose-response relationships for vitamin D with coronary heart disease, stroke, and all-cause mortality: observational and Mendelian randomisation analyses. nameOfConference DOI: 10.1016/s2213-8587(21)00263-1 QMRO: qmroHref Skrivankova VW, Richmond RC, Woolf BAR et al. (2021). Strengthening the Reporting of Observational Studies in Epidemiology Using Mendelian Randomization. nameOfConference DOI: 10.1001/jama.2021.18236 QMRO: qmroHref Skrivankova VW, Richmond RC, Woolf BAR et al. (publicationYear). Strengthening the reporting of observational studies in epidemiology using mendelian randomisation (STROBE-MR): explanation and elaboration. nameOfConference DOI: 10.1136/bmj.n2233 QMRO: qmroHref Kelly RS, Stewart ID, Bayne H et al. (2022). Metabolomic differences in lung function metrics: evidence from two cohorts. nameOfConference DOI: 10.1136/thoraxjnl-2020-216639 QMRO: qmroHref Evans RA, McAuley HJC, Harrison EM et al. (2021). Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study. nameOfConference DOI: 10.1016/s2213-2600(21)00383-0 QMRO: qmroHref Guida F, Tan VY, Corbin LJ et al. (publicationYear). The blood metabolome of incident kidney cancer: A case–control study nested within the MetKid consortium. nameOfConference DOI: 10.1371/journal.pmed.1003786 QMRO: qmroHref Lumbers RT, Shah S, Lin H et al. (2021). The genomics of heart failure: design and rationale of the HERMES consortium. nameOfConference DOI: 10.1002/ehf2.13517 QMRO: qmroHref Zhao J, Freathy R, Evans D et al. (2021). 586Effects of maternal circulating amino acids on offspring birthweight: a Mendelian randomisation analysis. nameOfConference DOI: 10.1093/ije/dyab168.757 QMRO: qmroHref Katsoulis M, Lai AG, Diaz-Ordaz K et al. (2021). Identifying adults at high-risk for change in weight and BMI in England: a longitudinal, large-scale, population-based cohort study using electronic health records. nameOfConference DOI: 10.1016/s2213-8587(21)00207-2 QMRO: qmroHref Wu H, Luan J, Forgetta V et al. (2021). Utility of Genetically Predicted Lp(a) (Lipoprotein [a]) and ApoB Levels for Cardiovascular Risk Assessment. nameOfConference DOI: 10.1161/circgen.121.003312 QMRO: qmroHref Higgins H, Mason AM, Larsson SC et al. (2021). Estimating the Population Benefits of Blood Pressure Lowering: A Wide‐Angled Mendelian Randomization Study in UK Biobank. nameOfConference DOI: 10.1161/jaha.121.021098 QMRO: qmroHref Bowker N, Hansford R, Burgess S et al. (2021). Genetically Predicted Glucose-Dependent Insulinotropic Polypeptide (GIP) Levels and Cardiovascular Disease Risk Are Driven by Distinct Causal Variants in the GIPR Region. nameOfConference DOI: 10.2337/db21-0103 QMRO: qmroHref Cai N, Gomez-Duran A, Yonova-Doing E et al. (2021). Mitochondrial DNA variants modulate N-formylmethionine, proteostasis and risk of late-onset human diseases. nameOfConference DOI: 10.1038/s41591-021-01441-3 QMRO: qmroHref Ruth KS, Day FR, Hussain J et al. (2021). Genetic insights into biological mechanisms governing human ovarian ageing. nameOfConference DOI: 10.1038/s41586-021-03779-7 QMRO: qmroHref Katsoulis M, Stavola BD, Diaz-Ordaz K et al. (2021). Weight Change and the Onset of Cardiovascular Diseases: Emulating Trials Using Electronic Health Records. nameOfConference DOI: 10.1097/ede.0000000000001393 QMRO: qmroHref Zhao Y, Stankovic S, Koprulu M et al. (publicationYear). GIGYF1 loss of function is associated with clonal mosaicism and adverse metabolic health. nameOfConference DOI: 10.1038/s41467-021-24504-y QMRO: qmroHref Heijmans BT, ‘t Hoen PAC, van Meurs J et al. (2021). Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour. nameOfConference DOI: 10.1038/s41562-021-01135-3 QMRO: qmroHref Chen J, Spracklen CN, Marenne G et al. (2021). The trans-ancestral genomic architecture of glycemic traits. nameOfConference DOI: 10.1038/s41588-021-00852-9 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/72348 Cheng TS, Day FR, Perry JRB et al. (publicationYear). Prepubertal Dietary and Plasma Phospholipid Fatty Acids Related to Puberty Timing: Longitudinal Cohort and Mendelian Randomization Analyses. nameOfConference DOI: 10.3390/nu13061868 QMRO: qmroHref Gaziano L, Giambartolomei C, Pereira AC et al. (2021). Actionable druggable genome-wide Mendelian randomization identifies repurposing opportunities for COVID-19. nameOfConference DOI: 10.1038/s41591-021-01310-z QMRO: qmroHref Perry BI, Stochl J, Upthegrove R et al. (2021). Longitudinal Trends in Childhood Insulin Levels and Body Mass Index and Associations With Risks of Psychosis and Depression in Young Adults. nameOfConference DOI: 10.1001/jamapsychiatry.2020.4180 QMRO: qmroHref Lotta L, Langenberg C, Wareham NJ et al. (2021). Reply to Unreliability of genotyping arrays for detecting very rare variants in human genetic studies: Example from a recent study of MC4R. nameOfConference DOI: 10.1016/j.cell.2021.03.014 QMRO: qmroHref Surendran P, Feofanova EV, Lahrouchi N et al. (2021). Publisher Correction: Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals. nameOfConference DOI: 10.1038/s41588-021-00832-z QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/79425 Perry BI, Burgess S, Jones HJ et al. (publicationYear). The potential shared role of inflammation in insulin resistance and schizophrenia: A bidirectional two-sample mendelian randomization study. nameOfConference DOI: 10.1371/journal.pmed.1003455 QMRO: qmroHref Pietzner M, Stewart ID, Raffler J et al. (2021). Plasma metabolites to profile pathways in noncommunicable disease multimorbidity. nameOfConference DOI: 10.1038/s41591-021-01266-0 QMRO: qmroHref Bonelli R, Ansell BRE, Lotta L et al. (2021). Genetic disruption of serine biosynthesis is a key driver of macular telangiectasia type 2 aetiology and progression. nameOfConference DOI: 10.1186/s13073-021-00848-4 QMRO: qmroHref Zhou S, Butler-Laporte G, Nakanishi T et al. (2021). A Neanderthal OAS1 isoform protects individuals of European ancestry against COVID-19 susceptibility and severity. nameOfConference DOI: 10.1038/s41591-021-01281-1 QMRO: qmroHref Lagou V, Mägi R, Hottenga J-J et al. (publicationYear). Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability. nameOfConference DOI: 10.1038/s41467-021-21276-3 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/70440 Pietzner M, Wheeler E, Carrasco-Zanini J et al. (publicationYear). Author Correction: Genetic architecture of host proteins involved in SARS-CoV-2 infection. nameOfConference DOI: 10.1038/s41467-021-21370-6 QMRO: qmroHref Brunner EJ, Maruyama K, Shipley M et al. (2021). Correction: Appetite disinhibition rather than hunger explains genetic effects on adult BMI trajectory. nameOfConference DOI: 10.1038/s41366-021-00770-0 QMRO: qmroHref Jones G, Trajanoska K, Santanasto AJ et al. (publicationYear). Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women. nameOfConference DOI: 10.1038/s41467-021-20918-w QMRO: qmroHref Georgakis MK, Harshfield EL, Malik R et al. (2021). Diabetes Mellitus, Glycemic Traits, and Cerebrovascular Disease: A Mendelian Randomization Study. nameOfConference DOI: 10.1212/wnl.0000000000011555 QMRO: qmroHref Brunner EJ, Maruyama K, Shipley M et al. (2021). Appetite disinhibition rather than hunger explains genetic effects on adult BMI trajectory. nameOfConference DOI: 10.1038/s41366-020-00735-9 QMRO: qmroHref Lotta LA, Pietzner M, Stewart ID et al. (2021). A cross-platform approach identifies genetic regulators of human metabolism and health. nameOfConference DOI: 10.1038/s41588-020-00751-5 QMRO: qmroHref Lagou V, Mägi R, Hottenga J-J et al. (publicationYear). Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability. nameOfConference DOI: 10.1038/s41467-020-19366-9 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/70439 Zhao J, Freathy R, Evans D et al. (2021). Effects of maternal circulating amino acids on offspring birthweight: a Mendelian randomisation analysis. nameOfConference DOI: doi QMRO: qmroHref Pietzner M, Wheeler E, Carrasco-Zanini J et al. (publicationYear). Genetic architecture of host proteins involved in SARS-CoV-2 infection. nameOfConference DOI: 10.1038/s41467-020-19996-z QMRO: qmroHref Surendran P, Feofanova EV, Lahrouchi N et al. (2020). Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals. nameOfConference DOI: 10.1038/s41588-020-00713-x QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/69571 Zheng J-S, Luan J, Sofianopoulou E et al. (2021). Plasma Vitamin C and Type 2 Diabetes: Genome-Wide Association Study and Mendelian Randomization Analysis in European Populations. nameOfConference DOI: 10.2337/dc20-1328 QMRO: qmroHref Cai L, Wheeler E, Kerrison ND et al. (publicationYear). Genome-wide association analysis of type 2 diabetes in the EPIC-InterAct study. nameOfConference DOI: 10.1038/s41597-020-00716-7 QMRO: qmroHref John C, Guyatt AL, Shrine N et al. (2020). A genome-wide association study of asthma-COPD overlap syndrome (ACOS). Genes and environment DOI: 10.1183/13993003.congress-2020.4919 QMRO: qmroHref Bowker N, Shah RL, Sharp SJ et al. (2020). Meta-analysis investigating the role of interleukin-6 mediated inflammation in type 2 diabetes. nameOfConference DOI: 10.1016/j.ebiom.2020.103062 QMRO: qmroHref Zheng J-S, Luan J, Sofianopoulou E et al. (publicationYear). The association between circulating 25-hydroxyvitamin D metabolites and type 2 diabetes in European populations: A meta-analysis and Mendelian randomisation analysis. nameOfConference DOI: 10.1371/journal.pmed.1003394 QMRO: qmroHref Zanini JC, Pietzner M, Langenberg C (2020). Integrating Genetics and the Plasma Proteome to Predict the Risk of Type 2 Diabetes. nameOfConference DOI: 10.1007/s11892-020-01340-w QMRO: qmroHref Zhou S, Morris JA, Oerton E et al. (2020). Large-scale genomics and proteomics to identify novel circulating biomarkers for bone density. nameOfConference DOI: 10.1016/j.bonr.2020.100338 QMRO: qmroHref Yaghootkar H, Zhang Y, Spracklen CN et al. (2020). Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity. nameOfConference DOI: 10.2337/db20-0070 QMRO: qmroHref Kulyté A, Lundbäck V, Lindgren CM et al. (2020). Corrigendum to “Genome-wide association study of adipocyte lipolysis in the GENetics of adipocyte lipolysis (GENiAL) cohort” [Molecular Metabolism 34 (2020) 85–96]. nameOfConference DOI: 10.1016/j.molmet.2020.101072 QMRO: qmroHref Teo K, Abeysekera KWM, Adams L et al. (2021). rs641738C>T near MBOAT7 is associated with liver fat, ALT and fibrosis in NAFLD: A meta-analysis. nameOfConference DOI: 10.1016/j.jhep.2020.08.027 QMRO: qmroHref Mann JP, Pietzner M, Wittemans LB et al. (2020). Insights into genetic variants associated with NASH-fibrosis from metabolite profiling. nameOfConference DOI: 10.1093/hmg/ddaa162 QMRO: qmroHref Moll M, Sakornsakolpat P, Shrine N et al. (2020). Chronic obstructive pulmonary disease and related phenotypes: polygenic risk scores in population-based and case-control cohorts. nameOfConference DOI: 10.1016/s2213-2600(20)30101-6 QMRO: qmroHref Messner CB, Demichev V, Wendisch D et al. (2020). Ultra-High-Throughput Clinical Proteomics Reveals Classifiers of COVID-19 Infection. nameOfConference DOI: 10.1016/j.cels.2020.05.012 QMRO: qmroHref Marenne G, Hendricks AE, Perdikari A et al. (2020). Exome Sequencing Identifies Genes and Gene Sets Contributing to Severe Childhood Obesity, Linking PHIP Variants to Repressed POMC Transcription. nameOfConference DOI: 10.1016/j.cmet.2020.05.007 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/74302 Fawcett KA, Obeidat M, Melbourne C et al. (publicationYear). Variants associated with HHIP expression have sex-differential effects on lung function. nameOfConference DOI: 10.12688/wellcomeopenres.15846.1 QMRO: qmroHref Perry B, Burgess S, Jones H et al. (2020). M88. EVIDENCE FOR INFLAMMATION AS A PUTATIVE SHARED MECHANISM FOR INSULIN RESISTANCE AND SCHIZOPHRENIA. nameOfConference DOI: 10.1093/schbul/sbaa030.400 QMRO: qmroHref Banerjee A, Pasea L, Harris S et al. (2020). Estimating excess 1-year mortality associated with the COVID-19 pandemic according to underlying conditions and age: a population-based cohort study. nameOfConference DOI: 10.1016/s0140-6736(20)30854-0 QMRO: qmroHref Meddens SFW, de Vlaming R, Bowers P et al. (2021). Genomic analysis of diet composition finds novel loci and associations with health and lifestyle. nameOfConference DOI: 10.1038/s41380-020-0697-5 QMRO: qmroHref Mehta NS, Mytton OT, Mullins EWS et al. (2020). SARS-CoV-2 (COVID-19): What Do We Know About Children? A Systematic Review. nameOfConference DOI: 10.1093/cid/ciaa556 QMRO: qmroHref Ostroff R, Langenberg C, Wareham N et al. (2020). PLASMA PROTEIN SCANNING AS A NEW TOOL IN PREVENTIVE CARDIOLOGY. nameOfConference DOI: 10.1016/s0735-1097(20)32646-2 QMRO: qmroHref Li C, Stoma S, Lotta LA et al. (2020). Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length. nameOfConference DOI: 10.1016/j.ajhg.2020.02.006 QMRO: qmroHref Manousaki D, Mitchell R, Dudding T et al. (2020). Genome-wide Association Study for Vitamin D Levels Reveals 69 Independent Loci. nameOfConference DOI: 10.1016/j.ajhg.2020.01.017 QMRO: qmroHref Ruth KS, Day FR, Tyrrell J et al. (2020). Using human genetics to understand the disease impacts of testosterone in men and women. nameOfConference DOI: 10.1038/s41591-020-0751-5 QMRO: qmroHref Kulyté A, Lundbäck V, Lindgren CM et al. (2020). Genome-wide association study of adipocyte lipolysis in the GENetics of adipocyte lipolysis (GENiAL) cohort. nameOfConference DOI: 10.1016/j.molmet.2020.01.009 QMRO: qmroHref Zuber V, Gill D, Ala-Korpela M et al. (2021). High-throughput multivariable Mendelian randomization analysis prioritizes apolipoprotein B as key lipid risk factor for coronary artery disease. nameOfConference DOI: 10.1093/ije/dyaa216 QMRO: qmroHref Shah S, Henry A, Roselli C et al. (publicationYear). Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure. nameOfConference DOI: 10.1038/s41467-019-13690-5 QMRO: qmroHref Georgakis M, Harshfield E, Malik R et al. (2020). DIABETES MELLITUS, GLYCEMIC TRAITS, AND CEREBROVASCULAR DISEASE: A MENDELIAN RANDOMIZATION STUDY. nameOfConference DOI: doi QMRO: qmroHref Perry B, Burgess S, Jones H et al. (2020). EVIDENCE FOR INFLAMMATION AS A PUTATIVE SHARED MECHANISM FOR INSULIN RESISTANCE AND SCHIZOPHRENIA. nameOfConference DOI: doi QMRO: qmroHref John C, Guyatt AL, Shrine N et al. (2020). Genome-wide association study of asthma-COPD overlap syndrome identifies new signals of association. nameOfConference DOI: doi QMRO: qmroHref Macdonald-Dunlop E, Joshi P, Peters J et al. (2020). Genomic Architecture of 184 Plasma Proteins in 18,884 Individuals: the SCALLOP Consortium. nameOfConference DOI: doi QMRO: qmroHref van Dam AD, Toledo EM, Loh NY et al. (2020). Hedgehog signalling as a determinant of human fat expansion and distribution. nameOfConference DOI: doi QMRO: qmroHref Zhou S, Oerton E, Morris J et al. (2020). Identifying circulating biomarkers for osteoporosis. nameOfConference DOI: doi QMRO: qmroHref Williams SA, Kivimaki M, Langenberg C et al. (2019). Plasma protein patterns as comprehensive indicators of health. nameOfConference DOI: 10.1038/s41591-019-0665-2 QMRO: qmroHref Chen Z, Yu H, Shi X et al. (2020). Functional Screening of Candidate Causal Genes for Insulin Resistance in Human Preadipocytes and Adipocytes. nameOfConference DOI: 10.1161/circresaha.119.315246 QMRO: qmroHref Hertel J, Harms AC, Heinken A et al. (2019). Integrated Analyses of Microbiome and Longitudinal Metabolome Data Reveal Microbial-Host Interactions on Sulfur Metabolism in Parkinson’s Disease. nameOfConference DOI: 10.1016/j.celrep.2019.10.035 QMRO: qmroHref Rolandsson O, Hampe CS, Sharp SJ et al. (2020). Autoimmunity plays a role in the onset of diabetes after 40 years of age. nameOfConference DOI: 10.1007/s00125-019-05016-3 QMRO: qmroHref Clark DW, Okada Y, Moore KHS et al. (2019). Associations of autozygosity with a broad range of human phenotypes.. nameOfConference DOI: 10.1038/s41467-019-12283-6 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/61102 Schmidt AF, Holmes MV, Preiss D et al. (2019). Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9. nameOfConference DOI: 10.1186/s12872-019-1187-z QMRO: qmroHref (publicationYear). Quality of dietary fat and genetic risk of type 2 diabetes: individual participant data meta-analysis. nameOfConference DOI: 10.1136/bmj.l5612 QMRO: qmroHref Cardona A, Day FR, Perry JRB et al. (publicationYear). Epigenome-Wide Association Study of Incident Type 2 Diabetes in a British Population: EPIC-Norfolk Study.. nameOfConference DOI: 10.2337/db18-0290 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/61088 Spracklen CN, Karaderi T, Yaghootkar H et al. (2019). Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology. nameOfConference DOI: 10.1016/j.ajhg.2019.08.001 QMRO: qmroHref Imamura F, Schulze MB, Sharp SJ et al. (2019). Estimated Substitution of Tea or Coffee for Sugar-Sweetened Beverages Was Associated with Lower Type 2 Diabetes Incidence in Case–Cohort Analysis across 8 European Countries in the EPIC-InterAct Study. nameOfConference DOI: 10.1093/jn/nxz156 QMRO: qmroHref Playdon MC, Joshi AD, Tabung FK et al. (publicationYear). Metabolomics Analytics Workflow for Epidemiological Research: Perspectives from the Consortium of Metabolomics Studies (COMETS) †. nameOfConference DOI: 10.3390/metabo9070145 QMRO: qmroHref Mokry LE, Zhou S, Guo C et al. (publicationYear). Interleukin-18 as a drug repositioning opportunity for inflammatory bowel disease: A Mendelian randomization study. nameOfConference DOI: 10.1038/s41598-019-45747-2 QMRO: qmroHref Spracklen CN, Karaderi T, Yaghootkar H et al. (2019). Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology. nameOfConference DOI: 10.1016/j.ajhg.2019.05.002 QMRO: qmroHref Malik R, Chauhan G, Traylor M et al. (2019). Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. nameOfConference DOI: 10.1038/s41588-019-0449-0 QMRO: qmroHref Turcot V, Lu Y, Highland HM et al. (2019). Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. nameOfConference DOI: 10.1038/s41588-019-0447-2 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/61615 Neville MJ, Wittemans LBL, Pinnick KE et al. (publicationYear). Regional fat depot masses are influenced by protein-coding gene variants. nameOfConference DOI: 10.1371/journal.pone.0217644 QMRO: qmroHref Hilton C, Neville MJ, Wittemans LBL et al. (2019). MicroRNA-196a links human body fat distribution to adipose tissue extracellular matrix composition. nameOfConference DOI: 10.1016/j.ebiom.2019.05.047 QMRO: qmroHref Shrine N, Guyatt AL, Erzurumluoglu AM et al. (2019). Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. nameOfConference DOI: 10.1038/s41588-019-0438-3 QMRO: qmroHref De Silva NMG, Borges MC, Hingorani AD et al. (2019). Liver Function and Risk of Type 2 Diabetes: Bidirectional Mendelian Randomization Study. nameOfConference DOI: 10.2337/db18-1048 QMRO: qmroHref Warrington NM, Beaumont RN, Horikoshi M et al. (2019). Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors. nameOfConference DOI: 10.1038/s41588-019-0403-1 QMRO: qmroHref Jannasch F, Kröger J, Agnoli C et al. (2019). Generalizability of a Diabetes-Associated Country-Specific Exploratory Dietary Pattern Is Feasible Across European Populations. nameOfConference DOI: 10.1093/jn/nxz031 QMRO: qmroHref Key TJ, Appleby PN, Bradbury KE et al. (2019). Consumption of Meat, Fish, Dairy Products, Eggs and Risk of Ischemic Heart Disease: A Prospective Study of 7198 Incident Cases Among 409,885 Participants in the Pan-European EPIC Cohort. nameOfConference DOI: 10.1161/circulationaha.118.038813 QMRO: qmroHref Yang Y, van der Klaauw AA, Zhu L et al. (publicationYear). Steroid receptor coactivator-1 modulates the function of Pomc neurons and energy homeostasis. nameOfConference DOI: 10.1038/s41467-019-08737-6 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/74307 Sung YJ, de las Fuentes L, Winkler TW et al. (2019). A multi-ancestry genome-wide study incorporating gene–smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure. nameOfConference DOI: 10.1093/hmg/ddz070 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/59202 Lotta LA, Mokrosiński J, de Oliveira EM et al. (2019). Human Gain-of-Function MC4R Variants Show Signaling Bias and Protect against Obesity. nameOfConference DOI: 10.1016/j.cell.2019.03.044 QMRO: qmroHref Bentley AR, Sung YJ, Brown MR et al. (2019). Multi-ancestry genome-wide gene–smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. nameOfConference DOI: 10.1038/s41588-019-0378-y QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/58835 Wittemans LBL, Lotta LA, Oliver-Williams C et al. (publicationYear). Assessing the causal association of glycine with risk of cardio-metabolic diseases. nameOfConference DOI: 10.1038/s41467-019-08936-1 QMRO: qmroHref Sakornsakolpat P, Prokopenko D, Lamontagne M et al. (2019). Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations. nameOfConference DOI: 10.1038/s41588-018-0342-2 QMRO: qmroHref Shrine N, Guyatt AL, Erzurumluoglu AM et al. (2019). New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. nameOfConference DOI: 10.1038/s41588-018-0321-7 QMRO: qmroHref Dam V, van der Schouw YT, Onland-Moret NC et al. (2019). Association of menopausal characteristics and risk of coronary heart disease: a pan-European case–cohort analysis. nameOfConference DOI: 10.1093/ije/dyz016 QMRO: qmroHref Yu B, Zanetti KA, Temprosa M et al. (2019). The Consortium of Metabolomics Studies (COMETS): Metabolomics in 47 Prospective Cohort Studies. nameOfConference DOI: 10.1093/aje/kwz028 QMRO: qmroHref Justice AE, Karaderi T, Highland HM et al. (2019). Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution. nameOfConference DOI: 10.1038/s41588-018-0334-2 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/56167 Vissers LET, Sluijs I, van der Schouw YT et al. (2019). Dairy Product Intake and Risk of Type 2 Diabetes in EPIC-InterAct: A Mendelian Randomization Study. nameOfConference DOI: 10.2337/dc18-2034 QMRO: qmroHref de Vries PS, Brown MR, Bentley AR et al. (2019). Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. nameOfConference DOI: 10.1093/aje/kwz005 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/56171 Larsson SC, Traylor M, Burgess S et al. (2019). Serum magnesium and calcium levels in relation to ischemic stroke: Mendelian randomization study. nameOfConference DOI: 10.1212/wnl.0000000000007001 QMRO: qmroHref Kilpeläinen TO, Bentley AR, Noordam R et al. (publicationYear). Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity. nameOfConference DOI: 10.1038/s41467-018-08008-w QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/58847 Erzurumluoglu AM, Liu M, Jackson VE et al. (2020). Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci. nameOfConference DOI: 10.1038/s41380-018-0313-0 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/55829 Zhou S, Forgetta V, Richards JB et al. (2019). Circulating Protein Biomarkers for Osteoporosis: Results from a Mendelian Randomization Study. nameOfConference DOI: doi QMRO: qmroHref Lotta LA, Stewart I, Sharp S et al. (2019). Variation in the LPL gene, low density lipoprotein-cholesterol lowering alleles and risk of coronary disease and type 2 diabetes. nameOfConference DOI: doi QMRO: qmroHref Kraja AT, Liu C, Fetterman JL et al. (2019). Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits. nameOfConference DOI: 10.1016/j.ajhg.2018.12.001 QMRO: qmroHref Lotta LA, Wittemans LBL, Zuber V et al. (2018). Association of Genetic Variants Related to Gluteofemoral vs Abdominal Fat Distribution With Type 2 Diabetes, Coronary Disease, and Cardiovascular Risk Factors.. nameOfConference DOI: 10.1001/jama.2018.19329 QMRO: qmroHref Giri A, Hellwege JN, Keaton JM et al. (2019). Trans-ethnic association study of blood pressure determinants in over 750,000 individuals. nameOfConference DOI: 10.1038/s41588-018-0303-9 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/55066 Brazel DM, Jiang Y, Hughey JM et al. (2018). Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use. nameOfConference DOI: 10.1016/j.biopsych.2018.11.024 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/57046 Franceschini N, Giambartolomei C, de Vries PS et al. (publicationYear). GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes. nameOfConference DOI: 10.1038/s41467-018-07340-5 QMRO: qmroHref Evangelou E, Warren HR, Mosen-Ansorena D et al. (2018). Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.. nameOfConference DOI: 10.1038/s41588-018-0297-3 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/56068 Zheng J-S, Imamura F, Sharp SJ et al. (2019). Association of Plasma Vitamin D Metabolites With Incident Type 2 Diabetes: EPIC-InterAct Case-Cohort Study. nameOfConference DOI: 10.1210/jc.2018-01522 QMRO: qmroHref Iotchkova V, Huang J, Morris JA et al. (2018). Author Correction: Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps. nameOfConference DOI: 10.1038/s41588-018-0276-8 QMRO: qmroHref Melvin A, Lam B, Langenberg C et al. (publicationYear). Dominant-negative mutations in PPAR alpha are present in unselected human populations and have a metabolic signature. nameOfConference DOI: 10.1530/endoabs.59.p154 QMRO: qmroHref Ligthart S, Vaez A, Võsa U et al. (2018). Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders. nameOfConference DOI: 10.1016/j.ajhg.2018.09.009 QMRO: qmroHref Mahajan A, Taliun D, Thurner M et al. (2018). Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps. nameOfConference DOI: 10.1038/s41588-018-0241-6 QMRO: qmroHref Do KT, Wahl S, Raffler J et al. (2018). Characterization of missing values in untargeted MS-based metabolomics data and evaluation of missing data handling strategies. nameOfConference DOI: 10.1007/s11306-018-1420-2 QMRO: qmroHref Lotta LA, Stewart ID, Sharp SJ et al. (2018). Association of Genetically Enhanced Lipoprotein Lipase–Mediated Lipolysis and Low-Density Lipoprotein Cholesterol–Lowering Alleles With Risk of Coronary Disease and Type 2 Diabetes. nameOfConference DOI: 10.1001/jamacardio.2018.2866 QMRO: qmroHref Evangelou E, Warren HR, Mosen-Ansorena D et al. (2018). Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. nameOfConference DOI: 10.1038/s41588-018-0205-x QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/47343 Karamitri A, Plouffe B, Bonnefond A et al. (2018). Type 2 diabetes–associated variants of the MT2 melatonin receptor affect distinct modes of signaling. nameOfConference DOI: 10.1126/scisignal.aan6622 QMRO: qmroHref Lee JJ, Wedow R, Okbay A et al. (2018). Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. nameOfConference DOI: 10.1038/s41588-018-0147-3 QMRO: qmroHref Merino J, Dashti HS, Li SX et al. (2019). Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium. nameOfConference DOI: 10.1038/s41380-018-0079-4 QMRO: qmroHref Feitosa MF, Kraja AT, Chasman DI et al. (2018). Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.. nameOfConference DOI: 10.1371/journal.pone.0198166 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/41963 Langenberg C, Lotta LA (2018). Genomic insights into the causes of type 2 diabetes. nameOfConference DOI: 10.1016/s0140-6736(18)31132-2 QMRO: qmroHref Bonàs-Guarch S, Guindo-Martínez M, Miguel-Escalada I et al. (publicationYear). Publisher Correction: Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes. nameOfConference DOI: 10.1038/s41467-018-04170-3 QMRO: qmroHref Ricci C, Wood A, Muller D et al. (publicationYear). Alcohol intake in relation to non-fatal and fatal coronary heart disease and stroke: EPIC-CVD case-cohort study. nameOfConference DOI: 10.1136/bmj.k934 QMRO: qmroHref Rivas MA, Avila BE, Koskela J et al. (publicationYear). Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population. nameOfConference DOI: 10.1371/journal.pgen.1007329 QMRO: qmroHref Wittemans LBL, Lotta LA, Langenberg C (2018). Prioritising Risk Factors for Type 2 Diabetes: Causal Inference through Genetic Approaches. nameOfConference DOI: 10.1007/s11892-018-1009-1 QMRO: qmroHref Yarmolinsky J, Bonilla C, Haycock PC et al. (2018). Circulating Selenium and Prostate Cancer Risk: A Mendelian Randomization Analysis. nameOfConference DOI: 10.1093/jnci/djy081 QMRO: qmroHref Mahajan A, Wessel J, Willems SM et al. (2018). Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes. nameOfConference DOI: 10.1038/s41588-018-0084-1 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/56153 Wood AM, Kaptoge S, Butterworth AS et al. (2018). Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies. nameOfConference DOI: 10.1016/s0140-6736(18)30134-x QMRO: qmroHref Mann J, Allison M, Wittemans L et al. (2018). THU-447 Metabolomic patterns associated with known genetic variants for hepatic steatosis and non-alcoholic steatohepatitisidentify biomarkers that may be of utility in predicting adverse liver outcomes. nameOfConference DOI: 10.1016/s0168-8278(18)30882-1 QMRO: qmroHref Li SX, Imamura F, Schulze MB et al. (2018). Interplay between genetic predisposition, macronutrient intake and type 2 diabetes incidence: analysis within EPIC-InterAct across eight European countries. nameOfConference DOI: 10.1007/s00125-018-4586-2 QMRO: qmroHref Malik R, Chauhan G, Traylor M et al. (2018). Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. nameOfConference DOI: 10.1038/s41588-018-0058-3 QMRO: qmroHref Kröger J, Meidtner K, Stefan N et al. (2018). Circulating Fetuin-A and Risk of Type 2 Diabetes: A Mendelian Randomization Analysis. nameOfConference DOI: 10.2337/db17-1268 QMRO: qmroHref Mytton OT, Jackson C, Steinacher A et al. (publicationYear). The current and potential health benefits of the National Health Service Health Check cardiovascular disease prevention programme in England: A microsimulation study. nameOfConference DOI: 10.1371/journal.pmed.1002517 QMRO: qmroHref Sung YJ, Winkler TW, de las Fuentes L et al. (2018). A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. nameOfConference DOI: 10.1016/j.ajhg.2018.01.015 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/35963 Flannick J, Fuchsberger C, Mahajan A et al. (publicationYear). Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. nameOfConference DOI: 10.1038/sdata.2018.2 QMRO: qmroHref Bonàs-Guarch S, Guindo-Martínez M, Miguel-Escalada I et al. (publicationYear). Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes. nameOfConference DOI: 10.1038/s41467-017-02380-9 QMRO: qmroHref Jiang X, O’Reilly PF, Aschard H et al. (publicationYear). Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels. nameOfConference DOI: 10.1038/s41467-017-02662-2 QMRO: qmroHref Melvin A, Lam B, Langenberg C et al. (2018). Dominant negative variants in PPAR alpha have a metabolic fingerprint. nameOfConference DOI: doi QMRO: qmroHref Rolandsson O, Hampe CS, Sharp SJ et al. (2018). GAD65 autoantibodies are associated with incident diabetes in mid-life: the EPIC-InterAct study. nameOfConference DOI: doi QMRO: qmroHref Wright DJ, Day FR, Kerrison ND et al. (2018). Genomic and epigenetic signatures of mosaic Y chromosome loss highlight cell cycle genes and overlap with cancer susceptibility. nameOfConference DOI: doi QMRO: qmroHref Medina-Gomez C, Kemp JP, Trajanoska K et al. (2018). Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects. nameOfConference DOI: 10.1016/j.ajhg.2017.12.005 QMRO: qmroHref Turcot V, Lu Y, Highland HM et al. (2018). Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. nameOfConference DOI: 10.1038/s41588-017-0011-x QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/34563 Turcot V, Lu Y, Highland HM et al. (2017). Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.. nameOfConference DOI: 10.1038/s41588-018-0050-y QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/56169 Flannick J, Fuchsberger C, Mahajan A et al. (2017). Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.. nameOfConference DOI: 10.1038/sdata.2017.179 QMRO: qmroHref Mardinoglu A, Gogg S, Lotta LA et al. (2018). Elevated Plasma Levels of 3-Hydroxyisobutyric Acid Are Associated With Incident Type 2 Diabetes. nameOfConference DOI: 10.1016/j.ebiom.2017.12.008 QMRO: qmroHref Meidtner K, Podmore C, Kröger J et al. (2018). Interaction of Dietary and Genetic Factors Influencing Body Iron Status and Risk of Type 2 Diabetes Within the EPIC-InterAct Study. nameOfConference DOI: 10.2337/dc17-1080 QMRO: qmroHref Zheng J-S, Sharp SJ, Imamura F et al. (2017). Association between plasma phospholipid saturated fatty acids and metabolic markers of lipid, hepatic, inflammation and glycaemic pathways in eight European countries: a cross-sectional analysis in the EPIC-InterAct study. nameOfConference DOI: 10.1186/s12916-017-0968-4 QMRO: qmroHref Liu DJ, Peloso GM, Yu H et al. (2017). Exome-wide association study of plasma lipids in >300,000 individuals. nameOfConference DOI: 10.1038/ng.3977 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/28624 Imamura F, Sharp SJ, Koulman A et al. (publicationYear). A combination of plasma phospholipid fatty acids and its association with incidence of type 2 diabetes: The EPIC-InterAct case-cohort study. nameOfConference DOI: 10.1371/journal.pmed.1002409 QMRO: qmroHref Kraja AT, Cook JP, Warren HR et al. (2017). New Blood Pressure–Associated Loci Identified in Meta-Analyses of 475 000 Individuals. nameOfConference DOI: 10.1161/circgenetics.117.001778 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/56729 Strawbridge RJ, Silveira A, Hoed MD et al. (2017). Identification of a novel proinsulin-associated SNP and demonstration that proinsulin is unlikely to be a causal factor in subclinical vascular remodelling using Mendelian randomisation. nameOfConference DOI: 10.1016/j.atherosclerosis.2017.09.031 QMRO: qmroHref Wheeler E, Leong A, Liu C-T et al. (publicationYear). Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis. nameOfConference DOI: 10.1371/journal.pmed.1002383 QMRO: qmroHref Prins BP, Kuchenbaecker KB, Bao Y et al. (publicationYear). Genome-wide analysis of health-related biomarkers in the UK Household Longitudinal Study reveals novel associations. nameOfConference DOI: 10.1038/s41598-017-10812-1 QMRO: qmroHref Graff M, Scott RA, Justice AE et al. (publicationYear). Correction: Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults. nameOfConference DOI: 10.1371/journal.pgen.1006972 QMRO: qmroHref Brænne I, Zeng L, Willenborg C et al. (2017). Genomic correlates of glatiramer acetate adverse cardiovascular effects lead to a novel locus mediating coronary risk.. nameOfConference DOI: 10.1371/journal.pone.0182999 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/33383 Lassale C, Tzoulaki I, Moons KGM et al. (2018). Separate and combined associations of obesity and metabolic health with coronary heart disease: a pan-European case-cohort analysis. nameOfConference DOI: 10.1093/eurheartj/ehx448 QMRO: qmroHref Mardinoglu A, Stančáková A, Lotta LA et al. (2017). Plasma Mannose Levels Are Associated with Incident Type 2 Diabetes and Cardiovascular Disease. nameOfConference DOI: 10.1016/j.cmet.2017.07.006 QMRO: qmroHref Wain LV, Vaez A, Jansen R et al. (2017). Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney. nameOfConference DOI: 10.1161/hypertensionaha.117.09438 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/26603 Willems SM, Wright DJ, Day FR et al. (publicationYear). Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness. nameOfConference DOI: 10.1038/ncomms16015 QMRO: qmroHref Stolzenberg-Solomon RZ, Moore S, Ulrich C et al. (2017). Abstract 4238: COnsortium for METabolomics Studies (COMETS): leveraging resources to accelerate scientific discovery. nameOfConference DOI: 10.1158/1538-7445.am2017-4238 QMRO: qmroHref Larsson SC, Scott RA, Traylor M et al. (2017). Type 2 diabetes, glucose, insulin, BMI, and ischemic stroke subtypes. nameOfConference DOI: 10.1212/wnl.0000000000004173 QMRO: qmroHref Hendricks AE, Bochukova EG, Marenne G et al. (publicationYear). Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity.. nameOfConference DOI: 10.1038/s41598-017-03054-8 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/33964 Shungin D, Deng WQ, Varga TV et al. (publicationYear). Ranking and characterization of established BMI and lipid associated loci as candidates for gene-environment interactions. nameOfConference DOI: 10.1371/journal.pgen.1006812 QMRO: qmroHref Li SX, Imamura F, Ye Z et al. (2017). Interaction between genes and macronutrient intake on the risk of developing type 2 diabetes: systematic review and findings from European Prospective Investigation into Cancer (EPIC)-InterAct. nameOfConference DOI: 10.3945/ajcn.116.150094 QMRO: qmroHref Scott RA, Scott LJ, Mägi R et al. (2017). An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans. nameOfConference DOI: 10.2337/db16-1253 QMRO: qmroHref Tachmazidou I, Süveges D, Min JL et al. (2017). Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits.. nameOfConference DOI: 10.1016/j.ajhg.2017.04.014 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/34665 Mullin BH, Zhao JH, Brown SJ et al. (2017). Genome-wide association study meta-analysis for quantitative ultrasound parameters of bone identifies five novel loci for broadband ultrasound attenuation. nameOfConference DOI: 10.1093/hmg/ddx174 QMRO: qmroHref Graff M, Scott RA, Justice AE et al. (publicationYear). Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults. nameOfConference DOI: 10.1371/journal.pgen.1006528 QMRO: qmroHref Justice AE, Winkler TW, Feitosa MF et al. (2017). Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.. nameOfConference DOI: 10.1038/ncomms14977 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/33363 Day FR, Thompson DJ, Helgason H et al. (2017). Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk. nameOfConference DOI: 10.1038/ng.3841 QMRO: qmroHref Wright DJ, Day FR, Kerrison ND et al. (2017). Genetic variants associated with mosaic Y chromosome loss highlight cell cycle genes and overlap with cancer susceptibility. nameOfConference DOI: 10.1038/ng.3821 QMRO: qmroHref Manning A, Highland HM, Gasser J et al. (2017). A Low-Frequency Inactivating Akt2 Variant Enriched in the Finnish Population is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk.. nameOfConference DOI: 10.2337/db16-1329 QMRO: qmroHref Warren HR, Evangelou E, Cabrera CP et al. (2017). Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.. nameOfConference DOI: 10.1038/ng.3768 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/19169 Marouli E, Graff M, Medina-Gomez C et al. (2017). 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SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function. nameOfConference DOI: 10.1681/asn.2016020131 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/36376 Lotta LA, Scott RA, Sharp SJ et al. (publicationYear). Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis. nameOfConference DOI: 10.1371/journal.pmed.1002179 QMRO: qmroHref Schmidt AF, Swerdlow DI, Holmes MV et al. (2017). PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study. nameOfConference DOI: 10.1016/s2213-8587(16)30396-5 QMRO: qmroHref Schumann G, Liu C, O'Reilly P et al. (2016). KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference. nameOfConference DOI: 10.1073/pnas.1611243113 QMRO: qmroHref Ried JS, Jeff M J, Chu AY et al. (2016). 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A Systematic Review of Biomarkers and Risk of Incident Type 2 Diabetes: An Overview of Epidemiological, Prediction and Aetiological Research Literature. nameOfConference DOI: 10.1371/journal.pone.0163721 QMRO: qmroHref Horikoshi M, Beaumont RN, Day FR et al. (2016). Genome-wide associations for birth weight and correlations with adult disease.. nameOfConference DOI: 10.1038/nature19806 QMRO: qmroHref Lotta LA, Sharp SJ, Burgess S et al. (2016). Association Between Low-Density Lipoprotein Cholesterol–Lowering Genetic Variants and Risk of Type 2 Diabetes: A Meta-analysis. nameOfConference DOI: 10.1001/jama.2016.14568 QMRO: qmroHref The InterAct Consortium (2016). Investigation of gene–diet interactions in the incretin system and risk of type 2 diabetes: the EPIC-InterAct study. nameOfConference DOI: 10.1007/s00125-016-4090-5 QMRO: qmroHref MUNROE PB (2016). Trans-ancestry meta-analyses identify novel rare and common variants associated with blood pressure and hypertension. nameOfConference DOI: 10.1038/ng.3654 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/13707 MUNROE PB (publicationYear). The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. nameOfConference DOI: 10.1038/ng.3667 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/15563 Forouhi NG, Imamura F, Sharp SJ et al. (publicationYear). Association of Plasma Phospholipid n-3 and n-6 Polyunsaturated Fatty Acids with Type 2 Diabetes: The EPIC-InterAct Case-Cohort Study. nameOfConference DOI: 10.1371/journal.pmed.1002094 QMRO: qmroHref Walford GA, Gustafsson S, Rybin D et al. (2016). Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci. nameOfConference DOI: 10.2337/db16-0199 QMRO: qmroHref Fuchsberger C, Flannick J, Teslovich TM et al. (2016). The genetic architecture of type 2 diabetes. nameOfConference DOI: 10.1038/nature18642 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/23544 Winkler TW, Justice AE, Graff M et al. (2016). Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.. nameOfConference DOI: 10.1371/journal.pgen.1006166 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/35005 Charoen P, Nitsch D, Engmann J et al. (publicationYear). Mendelian Randomisation study of the influence of eGFR on coronary heart disease. nameOfConference DOI: 10.1038/srep28514 QMRO: qmroHref McLachlan S, Giambartolomei C, White J et al. (publicationYear). Replication and Characterization of Association between ABO SNPs and Red Blood Cell Traits by Meta-Analysis in Europeans. nameOfConference DOI: 10.1371/journal.pone.0156914 QMRO: qmroHref Scott RA, Freitag DF, Li L et al. (2016). A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease. nameOfConference DOI: 10.1126/scitranslmed.aad3744 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/13116 Yaghootkar H, Lotta LA, Tyrrell J et al. (2016). Genetic Evidence for a Link Between Favorable Adiposity and Lower Risk of Type 2 Diabetes, Hypertension, and Heart Disease. nameOfConference DOI: 10.2337/db15-1671 QMRO: qmroHref Albanes D, Moore S, Ulrich C et al. (2016). COnsortium for METabolomics Studies (COMETS): Leveraging Resources to Accelerate Scientific Discovery. nameOfConference DOI: 10.1096/fasebj.30.1_supplement.lb129 QMRO: qmroHref Zanoni P, Khetarpal SA, Larach DB et al. (2016). Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease. nameOfConference DOI: 10.1126/science.aad3517 QMRO: qmroHref Podmore C, Meidtner K, Schulze MB et al. (2016). Association of Multiple Biomarkers of Iron Metabolism and Type 2 Diabetes: The EPIC-InterAct Study. nameOfConference DOI: 10.2337/dc15-0257 QMRO: qmroHref Kilpeläinen TO, Carli JFM, Skowronski AA et al. (publicationYear). Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels. nameOfConference DOI: 10.1038/ncomms10494 QMRO: qmroHref Lu Y, Day FR, Gustafsson S et al. (publicationYear). New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk. nameOfConference DOI: 10.1038/ncomms10495 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/18699 White J, Sofat R, Hemani G et al. (2016). Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis. nameOfConference DOI: 10.1016/s2213-8587(15)00386-1 QMRO: qmroHref Yaghootkar H, Lotta L, Tyrrell J et al. (2016). Genetic Evidence for a Link between Favorable Adiposity and Lower Risk of Type 2 Diabetes, Hypertension, and Heart Disease. nameOfConference DOI: doi QMRO: qmroHref Luca LA, Scott RA, Sharp SJ et al. (2016). The interaction of insulin resistance and genetically-determined pancreatic response shapes the time trajectories of insulin secretion and glucose tolerance. nameOfConference DOI: doi QMRO: qmroHref Lunetta KL, Day FR, Sulem P et al. (publicationYear). Correction: Corrigendum: Rare coding variants and X-linked loci associated with age at menarche. nameOfConference DOI: 10.1038/ncomms10257 QMRO: qmroHref Teumer A, Tin A, Sorice R et al. (2016). Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes. nameOfConference DOI: 10.2337/db15-1313 QMRO: qmroHref Gaulton KJ, Ferreira T, Lee Y et al. (2015). Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci. nameOfConference DOI: 10.1038/ng.3437 QMRO: qmroHref Day FR, Ruth KS, Thompson DJ et al. (2015). Large-Scale Genomic Analyses Link Reproductive Aging to Hypothalamic Signaling, Breast Cancer Susceptibility, and BRCA1-Mediated DNA Repair. nameOfConference DOI: 10.1097/01.ogx.0000473766.71624.99 QMRO: qmroHref Lotta LA, Abbasi A, Sharp SJ et al. (2015). Definitions of Metabolic Health and Risk of Future Type 2 Diabetes in BMI Categories: A Systematic Review and Network Meta-analysis. nameOfConference DOI: 10.2337/dc15-1218 QMRO: qmroHref Winkler TW, Justice AE, Graff M et al. (publicationYear). The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. nameOfConference DOI: 10.1371/journal.pgen.1005378 QMRO: qmroHref Day FR, Ruth KS, Thompson DJ et al. (2015). Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. nameOfConference DOI: 10.1038/ng.3412 QMRO: qmroHref van Nielen M, Feskens EJM, Mensink M et al. (2015). Erratum. Dietary Protein Intake and Incidence of Type 2 Diabetes in Europe: The EPIC-InterAct Case-Cohort Study. Diabetes Care 2014;37:1854–1862. nameOfConference DOI: 10.2337/dc15-er10b QMRO: qmroHref Huang J, Howie B, McCarthy S et al. (publicationYear). Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel. nameOfConference DOI: 10.1038/ncomms9111 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/54488 Walter K, Min JL, Huang J et al. (2015). The UK10K project identifies rare variants in health and disease. nameOfConference DOI: 10.1038/nature14962 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/54492 Lunetta KL, Day FR, Sulem P et al. (publicationYear). Rare coding variants and X-linked loci associated with age at menarche. nameOfConference DOI: 10.1038/ncomms8756 QMRO: qmroHref Rolandsson O, Hampe CS, Wennberg P et al. (2015). Prevalence and Regional Distribution of Autoantibodies Against GAD65Ab in a European Population Without Diabetes: The EPIC-InterAct Study. nameOfConference DOI: 10.2337/dc15-0305 QMRO: qmroHref Nead KT, Sharp SJ, Thompson DJ et al. (2015). Evidence of a Causal Association Between Insulinemia and Endometrial Cancer: A Mendelian Randomization Analysis. nameOfConference DOI: 10.1093/jnci/djv178 QMRO: qmroHref Østergaard SD, Mukherjee S, Sharp SJ et al. (publicationYear). Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study. nameOfConference DOI: 10.1371/journal.pmed.1001841 QMRO: qmroHref The InterAct Consortium (2015). Dietary fibre and incidence of type 2 diabetes in eight European countries: the EPIC-InterAct Study and a meta-analysis of prospective studies. nameOfConference DOI: 10.1007/s00125-015-3585-9 QMRO: qmroHref Sluijs I, Holmes MV, van der Schouw YT et al. (2015). A Mendelian Randomization Study of Circulating Uric Acid and Type 2 Diabetes. nameOfConference DOI: 10.2337/db14-0742 QMRO: qmroHref Nelson CP, Hamby SE, Saleheen D et al. (2015). Genetically Determined Height and Coronary Artery Disease. nameOfConference DOI: 10.1056/nejmoa1404881 QMRO: qmroHref Benyamin B, Esko T, Ried JS et al. (publicationYear). Erratum: Corrigendum: Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis. nameOfConference DOI: 10.1038/ncomms7542 QMRO: qmroHref Drogan D, Dunn WB, Lin W et al. (2015). Untargeted Metabolic Profiling Identifies Altered Serum Metabolites of Type 2 Diabetes Mellitus in a Prospective, Nested Case Control Study. nameOfConference DOI: 10.1373/clinchem.2014.228965 QMRO: qmroHref Locke AE, Kahali B, Berndt SI et al. (2015). Genetic studies of body mass index yield new insights for obesity biology. nameOfConference DOI: 10.1038/nature14177 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/6989 Shungin D, Winkler TW, Croteau-Chonka DC et al. (2015). New genetic loci link adipose and insulin biology to body fat distribution. nameOfConference DOI: 10.1038/nature14132 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/7200 Shah AD, Langenberg C, Rapsomaniki E et al. (2015). Type 2 diabetes and incidence of a wide range of cardiovascular diseases: a cohort study in 1·9 million people. nameOfConference DOI: 10.1016/s0140-6736(15)60401-9 QMRO: qmroHref Wessel J, Chu AY, Willems SM et al. (publicationYear). Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility. nameOfConference DOI: 10.1038/ncomms6897 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/18365 Mahajan A, Sim X, Ng HJ et al. (publicationYear). Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus. nameOfConference DOI: 10.1371/journal.pgen.1004876 QMRO: qmroHref Pers TH, Karjalainen JM, Chan Y et al. (publicationYear). Biological interpretation of genome-wide association studies using predicted gene functions. nameOfConference DOI: 10.1038/ncomms6890 QMRO: qmroHref Jensen RB, Thankamony A, Day F et al. (2015). Genetic Markers of Insulin Sensitivity and Insulin Secretion Are Associated With Spontaneous Postnatal Growth and Response to Growth Hormone Treatment in Short SGA Children: the North European SGA Study (NESGAS). nameOfConference DOI: 10.1210/jc.2014-3469 QMRO: qmroHref Talmud PJ, Cooper JA, Morris RW et al. (2015). Sixty-Five Common Genetic Variants and Prediction of Type 2 Diabetes. nameOfConference DOI: 10.2337/db14-1504 QMRO: qmroHref Buijsse B, Boeing H, Drogan D et al. (2015). Consumption of fatty foods and incident type 2 diabetes in populations from eight European countries. nameOfConference DOI: 10.1038/ejcn.2014.249 QMRO: qmroHref Scott RA, Fall T, Pasko D et al. (2014). Common Genetic Variants Highlight the Role of Insulin Resistance and Body Fat Distribution in Type 2 Diabetes, Independent of Obesity. nameOfConference DOI: 10.2337/db14-0319 QMRO: qmroHref Herder C, Nuotio M-L, Shah S et al. (2014). Genetic Determinants of Circulating Interleukin-1 Receptor Antagonist Levels and Their Association With Glycemic Traits. nameOfConference DOI: 10.2337/db14-0731 QMRO: qmroHref Yaghootkar H, Scott RA, White CC et al. (2014). Genetic Evidence for a Normal-Weight “Metabolically Obese” Phenotype Linking Insulin Resistance, Hypertension, Coronary Artery Disease, and Type 2 Diabetes. nameOfConference DOI: 10.2337/db14-0318 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/12780 Shah AD, Langenberg C, Rapsomaniki E et al. (2015). Type 2 diabetes and incidence of cardiovascular diseases: a cohort study in 1·9 million people. nameOfConference DOI: 10.1016/s2213-8587(14)70219-0 QMRO: qmroHref Consortium TI, Spijkerman AMW, van der A DL et al. (2014). Smoking and Long-Term Risk of Type 2 Diabetes: The EPIC-InterAct Study in European Populations. nameOfConference DOI: 10.2337/dc14-1020 QMRO: qmroHref Wood AR, Esko T, Yang J et al. (2014). Defining the role of common variation in the genomic and biological architecture of adult human height. nameOfConference DOI: 10.1038/ng.3097 QMRO: qmroHref Benyamin B, Esko T, Ried JS et al. (publicationYear). Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis. nameOfConference DOI: 10.1038/ncomms5926 QMRO: qmroHref Wood AR, Esko T, Yang J et al. (2014). Defining the role of common variation in the genomic and biological architecture of adult human height. nameOfConference DOI: 10.1038/ng.3097 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/6379 Ye Z, Sharp SJ, Burgess S et al. (2015). Association between circulating 25-hydroxyvitamin D and incident type 2 diabetes: a mendelian randomisation study. nameOfConference DOI: 10.1016/s2213-8587(14)70184-6 QMRO: qmroHref Swerdlow DI, Preiss D, Kuchenbaecker KB et al. (2015). HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials. nameOfConference DOI: 10.1016/s0140-6736(14)61183-1 QMRO: qmroHref Holmes MV, Frikke-Schmidt R, Melis D et al. (2014). A systematic review and meta-analysis of 130,000 individuals shows smoking does not modify the association of APOE genotype on risk of coronary heart disease. nameOfConference DOI: 10.1016/j.atherosclerosis.2014.07.038 QMRO: qmroHref Ng MCY, Shriner D, Chen BH et al. (publicationYear). Meta-Analysis of Genome-Wide Association Studies in African Americans Provides Insights into the Genetic Architecture of Type 2 Diabetes. nameOfConference DOI: 10.1371/journal.pgen.1004517 QMRO: qmroHref Forouhi NG, Koulman A, Sharp SJ et al. (2014). Differences in the prospective association between individual plasma phospholipid saturated fatty acids and incident type 2 diabetes: the EPIC-InterAct case-cohort study. nameOfConference DOI: 10.1016/s2213-8587(14)70146-9 QMRO: qmroHref Hoggart CJ, Venturini G, Mangino M et al. (publicationYear). Novel Approach Identifies SNPs in SLC2A10 and KCNK9 with Evidence for Parent-of-Origin Effect on Body Mass Index. nameOfConference DOI: 10.1371/journal.pgen.1004508 QMRO: qmroHref Perry JRB, Day F, Elks CE et al. (2014). Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. nameOfConference DOI: 10.1038/nature13545 QMRO: qmroHref Holmes MV, Dale CE, Zuccolo L et al. (2014). Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data. nameOfConference DOI: 10.1136/bmj.g4164 QMRO: qmroHref van Nielen M, Feskens EJM, Mensink M et al. (2014). Dietary Protein Intake and Incidence of Type 2 Diabetes in Europe: The EPIC-InterAct Case-Cohort Study. nameOfConference DOI: 10.2337/dc13-2627 QMRO: qmroHref Langenberg C, Sharp SJ, Franks PW et al. (publicationYear). Gene-Lifestyle Interaction and Type 2 Diabetes: The EPIC InterAct Case-Cohort Study. nameOfConference DOI: 10.1371/journal.pmed.1001647 QMRO: qmroHref Dimas AS, Lagou V, Barker A et al. (2014). Impact of Type 2 Diabetes Susceptibility Variants on Quantitative Glycemic Traits Reveals Mechanistic Heterogeneity. nameOfConference DOI: 10.2337/db13-0949 QMRO: qmroHref Winkler TW, Day FR, Croteau-Chonka DC et al. (2014). Quality control and conduct of genome-wide association meta-analyses. nameOfConference DOI: 10.1038/nprot.2014.071 QMRO: qmroHref Prokopenko I, Poon W, Mägi R et al. (publicationYear). A Central Role for GRB10 in Regulation of Islet Function in Man. nameOfConference DOI: 10.1371/journal.pgen.1004235 QMRO: qmroHref Mahajan A, Go MJ, Zhang W et al. (2014). Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. nameOfConference DOI: 10.1038/ng.2897 QMRO: qmroHref Holmes MV, Asselbergs FW, Palmer TM et al. (2015). Mendelian randomization of blood lipids for coronary heart disease. nameOfConference DOI: 10.1093/eurheartj/eht571 QMRO: qmroHref Nead KT, Scott RA, Sharp SA et al. (2012). Abstract B76: Evidence of a causal association between fasting insulin concentrations and endometrial cancer: A Mendelian randomization analysis. nameOfConference DOI: 10.1158/1940-6207.prev-12-b76 QMRO: qmroHref Regnault N, Kleinman KP, Rifas-Shiman SL et al. (2014). Components of height and blood pressure in childhood. nameOfConference DOI: 10.1093/ije/dyt248 QMRO: qmroHref Scott RA, Fall T, Pasko D et al. (2014). Common Genetic Variants Highlight the Role of Insulin Resistance and Body Fat Distribution in Type 2 Diabetes, Independently of Obesity. nameOfConference DOI: doi QMRO: qmroHref Yaghootkar H, Scott R, White CC et al. (2014). Genetic Evidence for a Metabolically Obese, Normal Weight Phenotype That Links Insulin Resistance with Type 2 Diabetes, Hypertension, and Coronary Artery Disease. nameOfConference DOI: doi QMRO: qmroHref Claussnitzer M, Dankel SN, Klocke B et al. (2014). Leveraging Cross-Species Transcription Factor Binding Site Patterns: From Diabetes Risk Loci to Disease Mechanisms. nameOfConference DOI: 10.1016/j.cell.2013.10.058 QMRO: qmroHref Zamora-Ros R, Forouhi NG, Sharp SJ et al. (2014). Dietary Intakes of Individual Flavanols and Flavonols Are Inversely Associated with Incident Type 2 Diabetes in European Populations 1–3. nameOfConference DOI: 10.3945/jn.113.184945 QMRO: qmroHref Abbas S, Linseisen J, Rohrmann S et al. (2014). Dietary vitamin D intake and risk of type 2 diabetes in the European Prospective Investigation into Cancer and Nutrition: the EPIC-InterAct study. nameOfConference DOI: 10.1038/ejcn.2013.235 QMRO: qmroHref Zamora-Ros R, Forouhi NG, Sharp SJ et al. (2013). The Association Between Dietary Flavonoid and Lignan Intakes and Incident Type 2 Diabetes in European Populations The EPIC-InterAct study. nameOfConference DOI: 10.2337/dc13-0877 QMRO: qmroHref The InterAct Consortium (2014). Adherence to predefined dietary patterns and incident type 2 diabetes in European populations: EPIC-InterAct Study. nameOfConference DOI: 10.1007/s00125-013-3092-9 QMRO: qmroHref Do R, Willer CJ, Schmidt EM et al. (2013). Common variants associated with plasma triglycerides and risk for coronary artery disease. nameOfConference DOI: 10.1038/ng.2795 QMRO: qmroHref Global Lipids Genetics Consortium, Willer CJ, Schmidt EM et al. (2013). Discovery and refinement of loci associated with lipid levels.. nameOfConference DOI: 10.1038/ng.2797 QMRO: qmroHref Elks CE, Ong KK, Scott RA et al. (2013). Age at Menarche and Type 2 Diabetes Risk. nameOfConference DOI: 10.2337/dc13-0446 QMRO: qmroHref Kengne AP, Beulens JW, Peelen LM et al. (2014). Non-invasive risk scores for prediction of type 2 diabetes (EPIC-InterAct): a validation of existing models. nameOfConference DOI: 10.1016/s2213-8587(13)70103-7 QMRO: qmroHref Prudente S, Copetti M, Morini E et al. (2013). The SH2B1 obesity locus and abnormal glucose homeostasis: Lack of evidence for association from a meta-analysis in individuals of European ancestry. nameOfConference DOI: 10.1016/j.numecd.2013.05.001 QMRO: qmroHref Yaghootkar H, Lamina C, Scott RA et al. (2013). Mendelian Randomization Studies Do Not Support a Causal Role for Reduced Circulating Adiponectin Levels in Insulin Resistance and Type 2 Diabetes. nameOfConference DOI: 10.2337/db13-0128 QMRO: qmroHref Shah T, Engmann J, Dale C et al. (2013). Population Genomics of Cardiometabolic Traits: Design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium. nameOfConference DOI: 10.1371/journal.pone.0071345 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/6801 Hara K, Fujita H, Johnson TA et al. (2014). Genome-wide association study identifies three novel loci for type 2 diabetes. nameOfConference DOI: 10.1093/hmg/ddt399 QMRO: qmroHref Ahmad S, Rukh G, Varga TV et al. (2013). Gene × Physical Activity Interactions in Obesity: Combined Analysis of 111,421 Individuals of European Ancestry. nameOfConference DOI: 10.1371/journal.pgen.1003607 QMRO: qmroHref Hu Y-J, Berndt SI, Gustafsson S et al. (2013). Meta-analysis of Gene-Level Associations for Rare Variants Based on Single-Variant Statistics. nameOfConference DOI: 10.1016/j.ajhg.2013.06.011 QMRO: qmroHref Randall JC, Winkler TW, Kutalik Z et al. (2013). Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits. nameOfConference DOI: 10.1371/journal.pgen.1003500 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/19179 Ye Z, Gillson C, Sims M et al. (2013). The association of the mitochondrial DNA OriB variant (16184–16193 polycytosine tract) with type 2 diabetes in Europid populations. nameOfConference DOI: 10.1007/s00125-013-2945-6 QMRO: qmroHref van den Berg SW, van der A DL, Spijkerman AMW et al. (2013). The Association between Dietary Energy Density and Type 2 Diabetes in Europe: Results from the EPIC-InterAct Study. nameOfConference DOI: 10.1371/journal.pone.0059947 QMRO: qmroHref Tanaka T, Ngwa JS, van Rooij FJA et al. (2013). Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake 1 , 2 , 3 , 4. nameOfConference DOI: 10.3945/ajcn.112.052183 QMRO: qmroHref The InterAct consortium (2013). Consumption of sweet beverages and type 2 diabetes incidence in European adults: results from EPIC-InterAct. nameOfConference DOI: 10.1007/s00125-013-2899-8 QMRO: qmroHref Dastani Z, Johnson T, Kronenberg F et al. (2013). The shared allelic architecture of adiponectin levels and coronary artery disease. nameOfConference DOI: 10.1016/j.atherosclerosis.2013.03.034 QMRO: qmroHref Saxena R, Saleheen D, Been LF et al. (2013). Genome-Wide Association Study Identifies a Novel Locus Contributing to Type 2 Diabetes Susceptibility in Sikhs of Punjabi Origin From India. nameOfConference DOI: 10.2337/db12-1077 QMRO: qmroHref den Hoed M, Eijgelsheim M, Esko T et al. (2013). Identification of heart rate–associated loci and their effects on cardiac conduction and rhythm disorders. nameOfConference DOI: 10.1038/ng.2610 QMRO: qmroHref Paul DS, Albers CA, Rendon A et al. (2013). Maps of open chromatin highlight cell type–restricted patterns of regulatory sequence variation at hematological trait loci. nameOfConference DOI: 10.1101/gr.155127.113 QMRO: qmroHref Berndt SI, Gustafsson S, Mägi R et al. (2013). Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. nameOfConference DOI: 10.1038/ng.2606 QMRO: qmroHref (2013). Corrigendum. nameOfConference DOI: 10.1111/joim.12059 QMRO: qmroHref Brand JS, van der Schouw YT, Onland-Moret NC et al. (2013). Age at Menopause, Reproductive Life Span, and Type 2 Diabetes Risk Results from the EPIC-InterAct study. nameOfConference DOI: 10.2337/dc12-1020 QMRO: qmroHref Wennberg P, Rolandsson O, van der A DL et al. (2013). Self-rated health and type 2 diabetes risk in the European Prospective Investigation into Cancer and Nutrition-InterAct study: a case-cohort study. nameOfConference DOI: 10.1136/bmjopen-2012-002436 QMRO: qmroHref Gkrania-Klotsas E, Langenberg C, Sharp SJ et al. (2013). Seropositivity and Higher Immunoglobulin G Antibody Levels Against Cytomegalovirus Are Associated With Mortality in the Population-Based European Prospective Investigation of Cancer–Norfolk Cohort. nameOfConference DOI: 10.1093/cid/cit083 QMRO: qmroHref Talmud PJ, Shah S, Whittall R et al. (2013). Use of low-density lipoprotein cholesterol gene score to distinguish patients with polygenic and monogenic familial hypercholesterolaemia: a case-control study. nameOfConference DOI: 10.1016/s0140-6736(12)62127-8 QMRO: qmroHref Tabassum R, Chauhan G, Dwivedi OP et al. (2013). Genome-Wide Association Study for Type 2 Diabetes in Indians Identifies a New Susceptibility Locus at 2q21. nameOfConference DOI: 10.2337/db12-0406 QMRO: qmroHref Köttgen A, Albrecht E, Teumer A et al. (2013). Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. nameOfConference DOI: 10.1038/ng.2500 QMRO: qmroHref Sofat R, Mangione PP, Gallimore JR et al. (2013). Distribution and determinants of circulating complement factor H concentration determined by a high-throughput immunonephelometric assay. nameOfConference DOI: 10.1016/j.jim.2013.01.009 QMRO: qmroHref Smith CE, Ngwa J, Tanaka T et al. (2013). Lipoprotein receptor-related protein 1 variants and dietary fatty acids: meta-analysis of European origin and African American studies. nameOfConference DOI: 10.1038/ijo.2012.215 QMRO: qmroHref Scott RA, Pasko D, Fall T et al. (2013). A genetic risk score comprising common variants associated with fasting insulin is associated with OGTT- and clamp-based indices of whole body insulin sensitivity. nameOfConference DOI: doi QMRO: qmroHref Shah S, Casas J-P, Drenos F et al. (2013). Causal Relevance of Blood Lipid Fractions in the Development of Carotid Atherosclerosis. nameOfConference DOI: 10.1161/circgenetics.112.963140 QMRO: qmroHref Li H, Gan W, Lu L et al. (2013). A Genome-Wide Association Study Identifies GRK5 and RASGRP1 as Type 2 Diabetes Loci in Chinese Hans. nameOfConference DOI: 10.2337/db12-0454 QMRO: qmroHref van der Harst P, Zhang W, Mateo Leach I et al. (2012). Seventy-five genetic loci influencing the human red blood cell. nameOfConference DOI: 10.1038/nature11677 QMRO: qmroHref Deloukas P, Kanoni S, Willenborg C et al. (2013). Large-scale association analysis identifies new risk loci for coronary artery disease. nameOfConference DOI: 10.1038/ng.2480 QMRO: qmroHref consortium OBOTI, Sluijs I, Beulens JWJ et al. (2013). Dietary Glycemic Index, Glycemic Load, and Digestible Carbohydrate Intake Are Not Associated with Risk of Type 2 Diabetes in Eight European Countries. nameOfConference DOI: 10.3945/jn.112.165605 QMRO: qmroHref Albrechtsen A, Grarup N, Li Y et al. (2013). Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes. nameOfConference DOI: 10.1007/s00125-012-2756-1 QMRO: https://uat2-qmro.qmul.ac.uk/xmlui/handle/123456789/14570 Gertow K, Sennblad B, Strawbridge RJ et al. (2012). Identification of the BCAR1-CFDP1-TMEM170A Locus as a Determinant of Carotid Intima-Media Thickness and Coronary Artery Disease Risk. nameOfConference DOI: 10.1161/circgenetics.112.963660 QMRO: qmroHref Gkrania-Klotsas E, Langenberg C, Sharp SJ et al. (2012). Higher Immunoglobulin G Antibody Levels Against Cytomegalovirus Are Associated With Incident Ischemic Heart Disease in the Population-Based EPIC-Norfolk Cohort. nameOfConference DOI: 10.1093/infdis/jis620 QMRO: qmroHref The InterAct Consortium (2013). The link between family history and risk of type 2 diabetes is not explained by anthropometric, lifestyle or genetic risk factors: the EPIC-InterAct study. nameOfConference DOI: 10.1007/s00125-012-2715-x QMRO: qmroHref The InterAct Consortium (2013). Association between dietary meat consumption and incident type 2 diabetes: the EPIC-InterAct study. nameOfConference DOI: 10.1007/s00125-012-2718-7 QMRO: qmroHref Nürnberg ST, Rendon A, Smethurst PA et al. (2012). A GWAS sequence variant for platelet volume marks an alternative DNM3 promoter in megakaryocytes near a MEIS1 binding site. nameOfConference DOI: 10.1182/blood-2012-01-401893 QMRO: qmroHref Scott RA, Lagou V, Welch RP et al. (2012). Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. nameOfConference DOI: 10.1038/ng.2385 QMRO: qmroHref (2012). Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. nameOfConference DOI: 10.1038/ng.2383 QMRO: qmroHref Cooper AJ, Forouhi NG, Ye Z et al. (2012). Fruit and vegetable intake and type 2 diabetes: EPIC-InterAct prospective study and meta-analysis. nameOfConference DOI: 10.1038/ejcn.2012.85 QMRO: qmroHref Billings LK, Hsu Y-H, Ackerman RJ et al. (2012). Impact of Common Variation in Bone-Related Genes on Type 2 Diabetes and Related Traits. nameOfConference DOI: 10.2337/db11-1515 QMRO: qmroHref Okada Y, Sim X, Go MJ et al. (2012). Meta-analysis identifies multiple loci associated with kidney function–related traits in east Asian populations. nameOfConference DOI: 10.1038/ng.2352 QMRO: qmroHref Sluijs I, Forouhi NG, Beulens JW et al. (2012). The amount and type of dairy product intake and incident type 2 diabetes: results from the EPIC-InterAct Study. nameOfConference DOI: 10.3945/ajcn.111.021907 QMRO: qmroHref Langenberg C, Sharp SJ, Schulze MB et al. (2012). Long-Term Risk of Incident Type 2 Diabetes and Measures of Overall and Regional Obesity: The EPIC-InterAct Case-Cohort Study. nameOfConference DOI: 10.1371/journal.pmed.1001230 QMRO: qmroHref Perry JRB, Voight BF, Yengo L et al. (2012). Stratifying Type 2 Diabetes Cases by BMI Identifies Genetic Risk Variants in LAMA1 and Enrichment for Risk Variants in Lean Compared to Obese Cases. nameOfConference DOI: 10.1371/journal.pgen.1002741 QMRO: qmroHref van Woudenbergh GJ, Kuijsten A, Drogan D et al. (2012). Tea Consumption and Incidence of Type 2 Diabetes in Europe: The EPIC-InterAct Case-Cohort Study. nameOfConference DOI: 10.1371/journal.pone.0036910 QMRO: qmroHref Manning AK, Hivert M-F, Scott RA et al. (2012). A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. nameOfConference DOI: 10.1038/ng.2274 QMRO: qmroHref Fox CS, Liu Y, White CC et al. (2012). Genome-Wide Association for Abdominal Subcutaneous and Visceral Adipose Reveals a Novel Locus for Visceral Fat in Women. nameOfConference DOI: 10.1371/journal.pgen.1002695 QMRO: qmroHref Patel PS, Forouhi NG, Kuijsten A et al. (2012). The prospective association between total and type of fish intake and type 2 diabetes in 8 European countries: EPIC-InterAct Study. nameOfConference DOI: 10.3945/ajcn.111.029314 QMRO: qmroHref Beulens JWJ, van der Schouw YT, Bergmann MM et al. (2012). Alcohol consumption and risk of type 2 diabetes in European men and women: influence of beverage type and body sizeThe EPIC–InterAct study. nameOfConference DOI: 10.1111/j.1365-2796.2012.02532.x QMRO: qmroHref The InterAct Consortium (2012). Physical activity reduces the risk of incident type 2 diabetes in general and in abdominally lean and obese men and women: the EPIC–InterAct Study. nameOfConference DOI: 10.1007/s00125-012-2532-2 QMRO: qmroHref Forouhi NG, Ye Z, Rickard AP et al. (2012). Circulating 25-hydroxyvitamin D concentration and the risk of type 2 diabetes: results from the European Prospective Investigation into Cancer (EPIC)-Norfolk cohort and updated meta-analysis of prospective studies. nameOfConference DOI: 10.1007/s00125-012-2544-y QMRO: qmroHref Scott RA, Chu AY, Grarup N et al. (2012). No Interactions Between Previously Associated 2-Hour Glucose Gene Variants and Physical Activity or BMI on 2-Hour Glucose Levels. nameOfConference DOI: 10.2337/db11-0973 QMRO: qmroHref Kelly MA, Rees SD, Hydrie MZI et al. (2012). Circadian Gene Variants and Susceptibility to Type 2 Diabetes: A Pilot Study. nameOfConference DOI: 10.1371/journal.pone.0032670 QMRO: qmroHref Barker A, Langenberg C, Wareham NJ (2012). Genetic determinants of glucose homeostasis. nameOfConference DOI: 10.1016/j.beem.2011.12.002 QMRO: qmroHref Dastani Z, Hivert M-F, Timpson N et al. (2012). Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals. nameOfConference DOI: 10.1371/journal.pgen.1002607 QMRO: qmroHref Imamura M, Maeda S, Yamauchi T et al. (2012). A single-nucleotide polymorphism in ANK1 is associated with susceptibility to type 2 diabetes in Japanese populations. nameOfConference DOI: 10.1093/hmg/dds113 QMRO: qmroHref Stahl EA, Wegmann D, Trynka G et al. (2012). Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis. nameOfConference DOI: 10.1038/ng.2232 QMRO: qmroHref den Hoed M, Luan J, Langenberg C et al. (2013). Evaluation of common genetic variants identified by GWAS for early onset and morbid obesity in population-based samples. nameOfConference DOI: 10.1038/ijo.2012.34 QMRO: qmroHref Swerdlow DI, Holmes MV, Kuchenbaecker KB et al. (2012). The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis. nameOfConference DOI: 10.1016/s0140-6736(12)60110-x QMRO: qmroHref Cauchi S, Perry J, Almgren P et al. (2012). P128 Identification de nouveaux polymorphismes génétiques associés au risque de diabète de type 2 chez les obèses et non obèses européens. nameOfConference DOI: 10.1016/s1262-3636(12)71230-2 QMRO: qmroHref Demirkan A, van Duijn CM, Ugocsai P et al. (2012). Genome-Wide Association Study Identifies Novel Loci Associated with Circulating Phospho- and Sphingolipid Concentrations. nameOfConference DOI: 10.1371/journal.pgen.1002490 QMRO: qmroHref Bonnefond A, Clément N, Fawcett K et al. (2012). Rare MTNR1B variants impairing melatonin receptor 1B function contribute to type 2 diabetes. nameOfConference DOI: 10.1038/ng.1053 QMRO: qmroHref Marquez M, Huyvaert M, Perry JRB et al. (2012). Low-Frequency Variants in HMGA1 Are Not Associated With Type 2 Diabetes Risk. nameOfConference DOI: 10.2337/db11-0728 QMRO: qmroHref Gkrania-Klotsas E, Langenberg C, Tauriainen S et al. (2012). The association between prior infection with five serotypes of Coxsackievirus B and incident type 2 diabetes mellitus in the EPIC-Norfolk study. nameOfConference DOI: 10.1007/s00125-011-2443-7 QMRO: qmroHref Palmer ND, McDonough CW, Hicks PJ et al. (2012). A Genome-Wide Association Search for Type 2 Diabetes Genes in African Americans. nameOfConference DOI: 10.1371/journal.pone.0029202 QMRO: qmroHref Dimas AS, Gomes VI, Knowles J et al. (2012). Impact of Type 2 Diabetes Susceptibility Loci on Variation in Physiologic Glycaemic Traits in Non-Diabetic Individuals. nameOfConference DOI: doi QMRO: qmroHref Sacerdote C, Ricceri F, Rolandsson O et al. (2012). Lower educational level is a predictor of incident type 2 diabetes in European countries: the EPIC-InterAct study. nameOfConference DOI: 10.1093/ije/dys091 QMRO: qmroHref Yaghootkar H, Warren L, Lawlor D et al. (2012). Mendelian Randomization Studies to Understand the Role for Reduced Adiponectin Levels in Insulin Resistance or Type 2 Diabetes. nameOfConference DOI: doi QMRO: qmroHref Langenberg C, Ye Z, Gillson C et al. (2012). The association of the mitochondrial DNA 16184-16193 poly-C variant with type 2 diabetes. nameOfConference DOI: doi QMRO: qmroHref Cho YS, Chen C-H, Hu C et al. (2012). Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. nameOfConference DOI: 10.1038/ng.1019 QMRO: qmroHref Gieger C, Radhakrishnan A, Cvejic A et al. (2011). New gene functions in megakaryopoiesis and platelet formation. nameOfConference DOI: 10.1038/nature10659 QMRO: qmroHref The InterAct Consortium (2012). Validity of a short questionnaire to assess physical activity in 10 European countries. nameOfConference DOI: 10.1007/s10654-011-9625-y QMRO: qmroHref Bown MJ, Jones GT, Harrison SC et al. (2011). Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1. nameOfConference DOI: 10.1016/j.ajhg.2011.10.002 QMRO: qmroHref Bown MJ, Jones GT, Harrison SC et al. (2011). Abdominal Aortic Aneurysm Is Associated with a Variant in Low-Density Lipoprotein Receptor-Related Protein 1. nameOfConference DOI: 10.1016/j.ajhg.2011.10.002 QMRO: qmroHref Pfister R, Sharp S, Luben R et al. (2011). Mendelian Randomization Study of B-Type Natriuretic Peptide and Type 2 Diabetes: Evidence of Causal Association from Population Studies. nameOfConference DOI: 10.1371/journal.pmed.1001112 QMRO: qmroHref Chambers JC, Zhang W, Sehmi J et al. (2011). Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. nameOfConference DOI: 10.1038/ng.970 QMRO: qmroHref Strawbridge RJ, Dupuis J, Prokopenko I et al. (2011). Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes. nameOfConference DOI: 10.2337/db11-0415 QMRO: qmroHref Zhu H, Shyh-Chang N, Segrè AV et al. (2011). The Lin28/let-7 Axis Regulates Glucose Metabolism. nameOfConference DOI: 10.1016/j.cell.2011.08.033 QMRO: qmroHref Kanoni S, Nettleton JA, Hivert M-F et al. (2011). Total Zinc Intake May Modify the Glucose-Raising Effect of a Zinc Transporter (SLC30A8) Variant A 14-Cohort Meta-analysis. nameOfConference DOI: 10.2337/db11-0176 QMRO: qmroHref Romaguera D, Guevara M, Norat T et al. (2011). Mediterranean Diet and Type 2 Diabetes Risk in the European Prospective Investigation Into Cancer and Nutrition (EPIC) Study The InterAct project. nameOfConference DOI: 10.2337/dc11-0891 QMRO: qmroHref The InterAct Consortium (2011). Design and cohort description of the InterAct Project: an examination of the interaction of genetic and lifestyle factors on the incidence of type 2 diabetes in the EPIC Study. nameOfConference DOI: 10.1007/s00125-011-2182-9 QMRO: qmroHref Pfister R, Barnes D, Luben R et al. (2011). No evidence for a causal link between uric acid and type 2 diabetes: a Mendelian randomisation approach. nameOfConference DOI: 10.1007/s00125-011-2235-0 QMRO: qmroHref Kilpeläinen TO, Zillikens MC, Stančákova A et al. (2011). Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. nameOfConference DOI: 10.1038/ng.866 QMRO: qmroHref Pfister R, Barnes D, Luben RN et al. (2011). Individual and cumulative effect of type 2 diabetes genetic susceptibility variants on risk of coronary heart disease. nameOfConference DOI: 10.1007/s00125-011-2206-5 QMRO: qmroHref Barker A, Sharp SJ, Timpson NJ et al. (2011). Association of Genetic Loci With Glucose Levels in Childhood and Adolescence A Meta-Analysis of Over 6,000 Children. nameOfConference DOI: 10.2337/db10-1575 QMRO: qmroHref (2011). Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes. nameOfConference DOI: 10.1038/ng.833 QMRO: qmroHref Jensen AC, Barker A, Kumari M et al. (2011). Associations of Common Genetic Variants With Age-Related Changes in Fasting and Postload Glucose Evidence From 18 Years of Follow-Up of the Whitehall II Cohort. nameOfConference DOI: 10.2337/db10-1393 QMRO: qmroHref Langenberg C, Savage DB (2011). An amino acid profile to predict diabetes?. nameOfConference DOI: 10.1038/nm0411-418 QMRO: qmroHref Voight BF, Scott LJ, Steinthorsdottir V et al. (2011). Erratum: Corrigendum: Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. nameOfConference DOI: 10.1038/ng0411-388b QMRO: qmroHref Speliotes EK, Yerges-Armstrong LM, Wu J et al. (2011). Genome-Wide Association Analysis Identifies Variants Associated with Nonalcoholic Fatty Liver Disease That Have Distinct Effects on Metabolic Traits. nameOfConference DOI: 10.1371/journal.pgen.1001324 QMRO: qmroHref Soranzo N, Sanna S, Wheeler E et al. (2011). Common variants at 10 genomic loci influence hemoglobin A1C levels via glycemic and nonglycemic pathways (Diabetes (2010) 59, (3229-3239)). nameOfConference DOI: doi QMRO: qmroHref De Silva NMG, Freathy RM, Palmer TM et al. (2011). Mendelian Randomization Studies Do Not Support a Role for Raised Circulating Triglyceride Levels Influencing Type 2 Diabetes, Glucose Levels, or Insulin Resistance. nameOfConference DOI: 10.2337/db10-1317 QMRO: qmroHref (2011). Erratum. nameOfConference DOI: 10.2337/dc11-er03 QMRO: qmroHref Li S, Zhao JH, Luan J et al. (2011). Genetic predisposition to obesity leads to increased risk of type 2 diabetes. nameOfConference DOI: 10.1007/s00125-011-2044-5 QMRO: qmroHref Adler A, Langenberg C, Sims M et al. (2011). Are population-based carriers of a mutation associated with cystic fibrosis patients more likely to have diabetes?. nameOfConference DOI: doi QMRO: qmroHref Langenberg C, Wareham NJ (2011). Design and Cohort Description of the InterAct Project: An Examination of the Interaction of Genetic and Lifestyle Factors on the Incidence of Type 2 Diabetes in the EPIC Study. nameOfConference DOI: doi QMRO: qmroHref Scott RA, Manning AK, Hivert M-F et al. (2011). Genome-wide joint meta-analysis of SNP by BMI interaction on fasting insulin: a MAGIC study. nameOfConference DOI: doi QMRO: qmroHref Prokopenko I, Lagou V, Scott RA et al. (2011). Large-scale replication using "Metabochip" array identifies additional genetic loci influencing glycaemic traits. nameOfConference DOI: doi QMRO: qmroHref Langenberg C, Sharp SJ, Wareham NJ (2011). Long-term risk of type 2 diabetes and measures of overall and regional obesity: the European InterAct study. nameOfConference DOI: doi QMRO: qmroHref Forouhi NG, Ye Z, Rickard AP et al. (2011). The association and causal inference between circulating 25-hydroxy vitamin D concentration and the risk of type 2 diabetes. nameOfConference DOI: doi QMRO: qmroHref Gkrania-Klotsas E, Ye Z, Cooper AJ et al. (publicationYear). Differential White Blood Cell Count and Type 2 Diabetes: Systematic Review and Meta-Analysis of Cross-Sectional and Prospective Studies. nameOfConference DOI: 10.1371/journal.pone.0013405 QMRO: qmroHref Soranzo N, Sanna S, Wheeler E et al. (2010). Common Variants at 10 Genomic Loci Influence Hemoglobin A1C Levels via Glycemic and Nonglycemic Pathways. nameOfConference DOI: 10.2337/db10-0502 QMRO: qmroHref Nettleton JA, McKeown NM, Kanoni S et al. (2010). Interactions of Dietary Whole-Grain Intake With Fasting Glucose– and Insulin-Related Genetic Loci in Individuals of European Descent A meta-analysis of 14 cohort studies. nameOfConference DOI: 10.2337/dc10-1150 QMRO: qmroHref Teslovich TM, Musunuru K, Smith AV et al. (2010). Biological, clinical and population relevance of 95 loci for blood lipids. nameOfConference DOI: 10.1038/nature09270 QMRO: qmroHref Voight BF, Scott LJ, Steinthorsdottir V et al. (2010). Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. nameOfConference DOI: 10.1038/ng.609 QMRO: qmroHref Elks CE, Loos RJF, Sharp SJ et al. (publicationYear). Genetic Markers of Adult Obesity Risk Are Associated with Greater Early Infancy Weight Gain and Growth. nameOfConference DOI: 10.1371/journal.pmed.1000284 QMRO: qmroHref Dupuis J, Langenberg C, Prokopenko I et al. (2010). Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. nameOfConference DOI: 10.1038/ng0510-464a QMRO: qmroHref Liu C, Wu Y, Li H et al. (2010). MTNR1B rs10830963 is associated with fasting plasma glucose, HbA1Cand impaired beta-cell function in Chinese Hans from Shanghai. nameOfConference DOI: 10.1186/1471-2350-11-59 QMRO: qmroHref Dash S, Langenberg C, Fawcett KA et al. (2010). Analysis of TBC1D4 in patients with severe insulin resistance. nameOfConference DOI: 10.1007/s00125-010-1724-x QMRO: qmroHref Bouatia-Naji N, Saxena R, Hivert MF et al. (2010). O10 Une méta-analyse GWA de la glycémie après 2 h d’HGPO révèle que GIPR est associé avec la sécrétion de l’insuline en réponse au glucose et que ADCY5 est un nouveau gène de susceptibilité au diabète de type 2. nameOfConference DOI: 10.1016/s1262-3636(10)70014-8 QMRO: qmroHref Ingelsson E, Langenberg C, Hivert M-F et al. (2010). Detailed Physiologic Characterization Reveals Diverse Mechanisms for Novel Genetic Loci Regulating Glucose and Insulin Metabolism in Humans. nameOfConference DOI: 10.2337/db09-1568 QMRO: qmroHref Saxena R, Hivert M-F, Langenberg C et al. (2010). Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. nameOfConference DOI: 10.1038/ng.521 QMRO: qmroHref Dupuis J, Langenberg C, Prokopenko I et al. (2010). New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. nameOfConference DOI: 10.1038/ng.520 QMRO: qmroHref Langenberg C, Jensen AC, Barker A et al. (2010). Age-dependent genetic effects on post-load glucose during 18 years of follow-up of the Whitehall II Cohort. nameOfConference DOI: doi QMRO: qmroHref Nettleton JA, McKeown NM, Kanoni S et al. (2010). Interactions of Dietary Whole-Grain Intake With Fasting Glucose- and Insulin-Related Genetic Loci in Individuals of European Descent A meta-analysis of 14 cohort studies. nameOfConference DOI: 10.2337/dc10-1150 QMRO: qmroHref Richards JB, Waterworth D, O'Rahilly S et al. (2009). A Genome-Wide Association Study Reveals Variants in ARL15 that Influence Adiponectin Levels. nameOfConference DOI: 10.1371/journal.pgen.1000768 QMRO: qmroHref Weiss LA, Langenberg C, Barrett‐Connor E (2006). Ghrelin and Bone: Is There an Association in Older Adults?: The Rancho Bernardo Study*. nameOfConference DOI: 10.1359/jbmr.060209 QMRO: qmroHref Kong A, Steinthorsdottir V, Masson G et al. (2009). Parental origin of sequence variants associated with complex diseases. nameOfConference DOI: 10.1038/nature08625 QMRO: qmroHref Perry JRB, Weedon MN, Langenberg C et al. (2010). Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes. nameOfConference DOI: 10.1093/hmg/ddp522 QMRO: qmroHref Kelliny C, Ekelund U, Andersen LB et al. (2009). Common Genetic Determinants of Glucose Homeostasis in Healthy Children The European Youth Heart Study. nameOfConference DOI: 10.2337/db09-0374 QMRO: qmroHref Salanti G, Southam L, Altshuler D et al. (2009). Underlying Genetic Models of Inheritance in Established Type 2 Diabetes Associations. nameOfConference DOI: 10.1093/aje/kwp145 QMRO: qmroHref Dash S, Sano H, Rochford JJ et al. (2009). A truncation mutation in TBC1D4 in a family with acanthosis nigricans and postprandial hyperinsulinemia. nameOfConference DOI: 10.1073/pnas.0900909106 QMRO: qmroHref Langenberg C, Pascoe L, Mari A et al. (2009). Common genetic variation in the melatonin receptor 1B gene (MTNR1B) is associated with decreased early-phase insulin response. nameOfConference DOI: 10.1007/s00125-009-1392-x QMRO: qmroHref Wheeler E, Soranzo N, Sanna S et al. (2009). A Large Genome-wide Association Study of Glycated Hemoglobin Identifies Ten Common Variants not Mediated Through BMI. nameOfConference DOI: doi QMRO: qmroHref Elks C, Loos RJF, Davey-Smith G et al. (2009). Childhood Phenotypes Related to Adult Obesity: The Application of Genetic Risk Variants. nameOfConference DOI: doi QMRO: qmroHref Langenberg C, Saxena R, Hivert M-F et al. (2009). Genome-wide meta-analysis identifies novel genetic loci associated with OGTT-induced post-challenge glucose. nameOfConference DOI: doi QMRO: qmroHref Perry J, Zeggini E, Scott L et al. (2009). Mendelian Randomization Studies of the Role of Biomarkers in Type 2 Diabetes. nameOfConference DOI: doi QMRO: qmroHref Saxena R, Hivert M-F, Dupuis J et al. (2009). Meta-Analyses of Genome-Wide Association Studies for 2-Hour Glucose Levels during an Oral Glucose Tolerance Test Identify Novel Genetic Loci. nameOfConference DOI: doi QMRO: qmroHref Dupuis J, Langenberg C, Prokopenko I et al. (2009). Novel Genetic Loci Implicated in Fasting Glucose Homeostasis and Their Impact on Related Metabolic Traits. nameOfConference DOI: doi QMRO: qmroHref Prokopenko I, Dupuis J, Langenberg C et al. (2009). Novel genetic loci implicated in fasting glucose homeostasis and their impact on related metabolic traits. nameOfConference DOI: doi QMRO: qmroHref Prokopenko I, Hottenga JJ, Aulchenko YS et al. (2009). Variants in the DGKB Gene Influence Fasting Glucose Levels in Populations of European and East Asian Descent. nameOfConference DOI: doi QMRO: qmroHref Prokopenko I, Langenberg C, Florez JC et al. (2009). Variants in MTNR1B influence fasting glucose levels. nameOfConference DOI: 10.1038/ng.290 QMRO: qmroHref Zeggini E, Scott LJ, Saxena R et al. (2008). Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. nameOfConference DOI: 10.1038/ng.120 QMRO: qmroHref Hemingway H, Langenberg C, Damant J et al. (2008). Prevalence of Angina in Women Versus Men. nameOfConference DOI: 10.1161/circulationaha.107.720953 QMRO: qmroHref Jassal SK, Langenberg C, von Mühlen D et al. (2008). Usefulness of Microalbuminuria Versus the Metabolic Syndrome as a Predictor of Cardiovascular Disease in Women and Men >40 Years of Age (from the Rancho Bernardo Study). nameOfConference DOI: 10.1016/j.amjcard.2007.12.030 QMRO: qmroHref Batty GD, Gale CR, Mortensen LH et al. (2008). Pre-morbid intelligence, the metabolic syndrome and mortality: the Vietnam Experience Study. nameOfConference DOI: 10.1007/s00125-007-0908-5 QMRO: qmroHref Langenberg C, Loos RJF, Brage S et al. (2008). Novel type 2 diabetes susceptibility loci and measures of glycaemic control in a population based study of healthy children. nameOfConference DOI: doi QMRO: qmroHref Langenberg C, Araneta MRG, Bergstrom J et al. (2007). Diabetes and Coronary Heart Disease in Filipino-American Women Role of growth and life-course socioeconomic factors. nameOfConference DOI: 10.2337/dc06-1403 QMRO: qmroHref Skidmore PML, Hardy RJ, Kuh DJ et al. (2007). Life course body size and lipid levels at 53 years in a British birth cohort. nameOfConference DOI: 10.1136/jech.2006.047571 QMRO: qmroHref Perel P, Langenberg C, Ferrie J et al. (2006). Household Wealth and the Metabolic Syndrome in the Whitehall II Study. nameOfConference DOI: 10.2337/dc06-0022 QMRO: qmroHref Batty GD, Gunnell D, Langenberg C et al. (2006). Adult height and lung function as markers of life course exposures: Associations with risk factors and cause-specific mortality. nameOfConference DOI: 10.1007/s10654-006-9057-2 QMRO: qmroHref Langenberg C, Kuh D, Wadsworth MEJ et al. (2006). Social Circumstances and Education: Life Course Origins of Social Inequalities in Metabolic Risk in a Prospective National Birth Cohort. nameOfConference DOI: 10.2105/ajph.2004.049429 QMRO: qmroHref Laughlin GA, Barrett-Connor E, May S et al. (2007). Association of Adiponectin with Coronary Heart Disease and Mortality. nameOfConference DOI: 10.1093/aje/kwk001 QMRO: qmroHref Ferrie JE, Langenberg C, Shipley MJ et al. (2006). Birth weight, components of height and coronary heart disease: evidence from the Whitehall II study. nameOfConference DOI: 10.1093/ije/dyl184 QMRO: qmroHref Langenberg C, Bergstrom J, Scheidt-Nave C et al. (2006). Cardiovascular Death and the Metabolic Syndrome Role of adiposity-signaling hormones and inflammatory markers. nameOfConference DOI: 10.2337/dc05-2385 QMRO: qmroHref Langenberg C, Barrett-Connor E, Damant J et al. (2006). Sex differences in angina pectoris: meta-analysis of international variations in 53 studies in 23 countries. nameOfConference DOI: 10.1097/00149831-200605001-00126 QMRO: qmroHref Jassal SK, Langenberg C, Bergstrom J et al. (2006). Albuminuria improves prediction of cardiovascular disease mortality in older women with or without metabolic syndrome. nameOfConference DOI: doi QMRO: qmroHref Langenberg C, Allison M, Wong N et al. (2006). Aortic and coronary calcium in diabetic and nondiabetic men and women in the Multi-Ethnic Study of Atherosclerosis (MESA). nameOfConference DOI: doi QMRO: qmroHref Langenberg C, Bergstrom J, Von Mühlen D et al. (2006). Metabolic syndrome improves the prediction of coronary heart disease mortality in diabetes. nameOfConference DOI: doi QMRO: qmroHref Bergstrom J, Langenberg C, von Muhlen D et al. (2006). Novel risk factors do not improve prediction of cardiovascular mortality: Evidence from the Rancho Bernardo Study. nameOfConference DOI: doi QMRO: qmroHref Batty GD, Shipley MJ, Langenberg C et al. (2006). Adult height in relation to mortality from 14 cancer sites in men in London (UK): evidence from the original Whitehall study. nameOfConference DOI: 10.1093/annonc/mdj018 QMRO: qmroHref Langenberg C, Bergstrom J, Laughlin GA et al. (2005). Ghrelin, Adiponectin, and Leptin Do Not Predict Long-term Changes in Weight and Body Mass Index in Older Adults: Longitudinal Analysis of the Rancho Bernardo Cohort. nameOfConference DOI: 10.1093/aje/kwi338 QMRO: qmroHref Langenberg C, Bergstrom J, Laughlin GA et al. (2005). Ghrelin and the Metabolic Syndrome in Older Adults. nameOfConference DOI: 10.1210/jc.2005-1358 QMRO: qmroHref Perel P, Langenberg C, Ferrie J et al. (2005). 211-S: Household Wealth and the Metabolic Syndrome in the Whitehall II Cohort. nameOfConference DOI: 10.1093/aje/161.supplement_1.s53b QMRO: qmroHref (2005). Department of Error. nameOfConference DOI: 10.1016/s0140-6736(05)66509-9 QMRO: qmroHref Langenberg C, Hardy R, Breeze E et al. (2005). Influence of short stature on the change in pulse pressure, systolic and diastolic blood pressure from age 36 to 53 years: an analysis using multilevel models. nameOfConference DOI: 10.1093/ije/dyi071 QMRO: qmroHref Langenberg C, Shipley MJ, Batty GD et al. (2005). Adult Socioeconomic Position and the Association Between Height and Coronary Heart Disease Mortality: Findings From 33 Years of Follow-Up in the Whitehall Study. nameOfConference DOI: 10.2105/2004.046219 QMRO: qmroHref Kuh D, Langenberg C, Hardy R et al. (2005). Cardiovascular risk at age 53 years in relation to the menopause transition and use of hormone replacement therapy: a prospective British birth cohort study. nameOfConference DOI: 10.1111/j.1471-0528.2005.00416.x QMRO: qmroHref Hardy R, Kuh D, Langenberg C et al. (2005). Birthweight, childhood social class, and change in adult blood pressure in the 1946 British birth cohort (vol 362, pg 1178, 2003). nameOfConference DOI: doi QMRO: qmroHref Langenberg C, Bergstrom J, Barrett-Connor E (2005). Cardiovascular death and the metabolic syndrome: Role of inflammatory cytokines and adiposity signaling hormones. nameOfConference DOI: doi QMRO: qmroHref Langenberg C, Bergstrom J, Laughlin GA et al. (2005). Hormonal signals of weight homeostasis and 18-year weight change in older adults: Longitudinal analysis of the Rancho Bernardo cohort. nameOfConference DOI: doi QMRO: qmroHref Hardy R, Wadsworth MEJ, Langenberg C et al. (2004). Birthweight, childhood growth, and blood pressure at 43 years in a British birth cohort. nameOfConference DOI: 10.1093/ije/dyh027 QMRO: qmroHref Skidmore PML, Hardy RJ, Kuh DJ et al. (2004). Birth Weight and Lipids in a National Birth Cohort Study. nameOfConference DOI: 10.1161/01.atv.0000116692.85043.ef QMRO: qmroHref Hardy R, Langenberg C (2003). Commentary: The association between height growth and cholesterol levels during puberty: implications for adult health. nameOfConference DOI: 10.1093/ije/dyg315 QMRO: qmroHref Wadsworth MEJ, Butterworth SL, Hardy RJ et al. (2003). The life course prospective design: an example of benefits and problems associated with study longevity. nameOfConference DOI: 10.1016/s0277-9536(03)00083-2 QMRO: qmroHref Langenberg C, Hardy R, Kuh D et al. (2003). Central and total obesity in middle aged men and women in relation to lifetime socioeconomic status: evidence from a national birth cohort. nameOfConference DOI: 10.1136/jech.57.10.816 QMRO: qmroHref Hardy R, Kuh D, Langenberg C et al. (2003). Birthweight, childhood social class, and change in adult blood pressure in the 1946 British birth cohort. nameOfConference DOI: 10.1016/s0140-6736(03)14539-4 QMRO: qmroHref Langenberg C, Marmot M (2003). Commentary: Disentangling the association between short height and cardiovascular risk—genes or environment?. nameOfConference DOI: 10.1093/ije/dyg221 QMRO: qmroHref Langenberg C, Hardy R, Kuh D et al. (2003). Influence of height, leg and trunk length on pulse pressure, systolic and diastolic blood pressure. nameOfConference DOI: 10.1097/00004872-200303000-00019 QMRO: qmroHref Asif AR, Grunewald RW, Langenberg C et al. (2003). Human organic anion transporter 3 (hOAT3) in human adrenocortical cells transports cortisol. nameOfConference DOI: doi QMRO: qmroHref Kuh D, Hardy R, Langenberg C et al. (2002). Mortality in adults aged 26-54 years related to socioeconomic conditions in childhood and adulthood: post war birth cohort study. nameOfConference DOI: 10.1136/bmj.325.7372.1076 QMRO: qmroHref Pritsche L, Donner-Banzhoff N, Druck G et al. (2001). EbM-courses for hospital and practise settings - Current models in Germany. nameOfConference DOI: doi QMRO: qmroHref Helou A, Perleth M, Lühmann D et al. (2001). Evidence-based medicine: What kind of competencies should medical education provide?. nameOfConference DOI: doi QMRO: qmroHref Raspe H, Langenberg C (1999). Final and causal foundations of medical practice--two achievements of evidence-based medicine.. nameOfConference DOI: doi QMRO: qmroHref