Dr Ruth RoseLecturer in BiosciencesEmail: r.s.rose@qmul.ac.ukRoom Number: Fogg 4.34TeachingPublicationsUndergraduate Teaching Techniques in Biomedical Sciences (BMD 219) Advanced Biochemical Research Methods (BIO491) ResearchPublicationsPublications from the Protein Production Facility Rose, R-S., Richardson, K.H., Latvanen, E.J., Hanson, C.A., Resmini, M., Sanders, I.A. (2020) Microbial degradation of plastic in aqueous solutions demonstrated by CO2 evolution and quantification. IJMS. 21(4)1176. Younan, N.D., Chen, K.F., Rose, R.S., Crowther, D.C., Viles, J.H. (2018) Prion protein stabilizes amyloid- (A) oligomers and enhances A neurotoxicity in a Drosophila model of Alzheimer’s disease. JBC. 293: 13090-13099 Bridge, K. S., Shah, K. M., Li, Y., Foxler, D. E., Wong, S. C. K., Miller, D. C., Davidson, K. M., Foster, J. G., Rose, R., Hodgkinson, M. R., Ribeiro, P. S., Aboobaker, A. A., Yashiro, K., Wang, X., Graves, P. R., Plevin, M. J., Lagos, D., Sharp, T. V. (2017) Argonaute Utilization for miRNA Silencing Is Determined by Phosphorylation-Dependent Recruitment of LIM-Domain-Containing Proteins. Cell Reports. 20:173-187 Novoselova, T.V., Rose, R.S., Marks, H.M., Sullivan, J.A. (2013) SUMOylation regulates the Homologous to E6-AP Carboxy Terminus (HECT) ubiquitin ligase Rsp5p. JBC. 288: 10308-10317 Hamilton, M.L., Kuate, S.P., Brazier-Hicks, M., Caulfield, J.C., Rose, R., Edwards, R., Torto, B., Pickett, J.A., Hooper, A.M. (2012) Elucidation of the biosynthesis of the di-C-glycosylflavone isoschaftoside, an allelopathic component from Desmodium spp. that inhibits Striga spp. development. Phytochemistry. 84: 169-176 Waite, R.D., Rose, R.S., Rangarajan, M., Aduse-Opoku, J., Hashim, A., Curtis, M.A. (2012) Pseudomonas aeruginosa Possesses Two Putative Type I Signal Peptidases, LepB and PA1303, Each with Distinct Roles in Physiology and Virulence. Journal of Bacteriology. 194 (17): 4521-36 Novoselova, T.V., Zahira, K., Rose, R.S., Sullivan, J.A. (2012) Bul proteins, a nonredundant, antagonistic family of ubiquitin ligase regulatory proteins. Eukaryotic Cell. 11(4) 462-70 Research publications Hughes, M., Snetkov, V., Rose, R.-S., Trousil, S., Mermoud, J.E., Dingwall, C. (2010) Neurite-like structures induced by mevalonate pathway blockade are due to the stability of cell adhesion foci and are enhanced by the presence of APP. J. Neurochem. 114: 832-842 M.J. Warren, E. Deery and S. R. Rose (2009) Biosynthesis of Siroheme and Coenzyme F430. In M.J. Warren and A.G. Smith (Eds) Tetrapyrroles: Birth, life and Death (Molecular Biology Intelligence Unit) (Chp 22) Springer-Verlag: New York Schroeder, S., Lawrence, A.D., Biedendieck, R., Rose, R.S., Deery, E., Graham, R.M., McLean, K.J., Munro, A.W., Rigby, S.E.J., Warren, M.J. (2008) Demonstration that CobG, the monooxygenase associated with the ring contraction process of the aerobic cobalamin (Vitamin B12) biosynthetic pathway, contains as Fe-S center and a mononuclear non-heme iron center. JBC. 284 (8) 4796-4805 Schubert, H.L., Rose, R.S., Leech, H.K., Brindley, A.A., Hill, C.P., Rigby, S.E.J., Warren, M.J. (2008) Structure and function of SirC from Bacillus megaterium: a metal-binding precorrin-2 dehydrogenase. Biochem J. 415: 257-263 Opalaye, O.*, Rose, R-S.*, Whittaker, M.M., Woo, E.-J., Whittaker, J.W. and R.W. Pickersgill. (2006) Structural and spectroscopic studies shed light on the mechanism of oxalate oxidase. JBC. 281: 6428 – 6433 *joint authorship