Dr Sam Oxley

Profile

I was appointed in July 2021 as a clinical research fellow under the supervision of Professor Ranjit Manchanda, funded by the RoseTrees trust. 

My research is focused on the surgical prevention of ovarian and endometrial cancer in those at high risk. I am part of the central coordinating team of PROTECTOR, a study comparing surgical procedures in the prevention of ovarian cancer, and am conducting qualitative research into quality of life after surgery. 

I have an interest in the health economics of risk-reducing hysterectomy and other preventive strategies in endometrial cancer, and am leading the PRESCORES study. 

I also work on the Jewish Hereditary Cancer Review, UKCOGS, and other studies. 

Research

Publications

• Wei X, Oxley S, Sideris M, Kalra A, Brentnall A, Sun L, Yang L, Legood R, Manchanda R. Quality of life after risk-reducing surgery for breast and ovarian cancer prevention: a systematic review and meta-analysis. American Journal of Obstetrics and Gynecology. 2023 Apr 12.
• Gaba F, Blyuss O, Tan A, Munblit D, Oxley S, Khan K, Legood R, Manchanda R. Breast Cancer Risk and Breast-Cancer-Specific Mortality following Risk-Reducing Salpingo-Oophorectomy in BRCA Carriers: A Systematic Review and Meta-Analysis. Cancers. 2023 Mar 6;15(5):1625.
• Oxley S, Kalra A, Sideris M, Itzkowitz N, Evans O, Atakpa EC, Brentnall AR, Dworschak N, Gaba F, Gabe R, Sundar S. Impact of Multiple COVID-19 Waves on Gynaecological Cancer Services in the UK. Cancers. 2023 Feb 16;15(4):1273.
• Oxley S, Wei X, Sideris M, Manchanda R. Cost-Effectiveness of Genetic Testing Strategies for Breast Cancer. InScreening and Risk Reduction Strategies for Breast Cancer: Imaging Modality and Risk-Reduction Approaches 2023 Feb 24 (pp. 113-126). Singapore: Springer Nature Singapore.
• Oxley S, Xiong R, Wei X, Kalra A, Sideris M, Legood R, Manchanda R. Quality of Life after Risk-Reducing Hysterectomy for Endometrial Cancer Prevention: A Systematic Review. Cancers. 2022 Jan;14(23):5832. PMID 36497314
• Wei X, Oxley S, Sideris M, Kalra A, Sun L, Yang L, Legood R, Manchanda R. Cost-Effectiveness of Risk-Reducing Surgery for Breast and Ovarian Cancer Prevention: A Systematic Review. Cancers. 2022 Dec 12;14(24):6117. PMID 36551605
• Oxley S, Gaba F, Liu X, Yang X, Chandrasekaran D, Kalsi J, Antoniou A, Side L, Sanderson S, Waller J, Ahmed M. Unselected Population Genetic Testing for Personalised Ovarian Cancer Risk Prediction: A Qualitative Study Using Semi-Structured Interviews. Diagnostics. 2022 May;12(5):1028. PMID 35626184
• Oxley SG, Manchanda R, Sundar S, Ghaem-Maghami, S. COVID-19 and the impact on gynecologic cancer care. Int J Gynaecol Obstet. 2021 Oct;155 Suppl 1:94-101. doi: 10.1002/ijgo.13868. PMID: 34669200.
• Oxley SG, Achampong YA, Sambandan N, Hughes DJ, Thomas M, Lockley M, Olaitan A. Venous thromboembolism in women with ovarian cancer undergoing neoadjuvant chemotherapy prior to cytoreductive surgery: A retrospective study. Acta Obstet Gynecol Scand. 2021 Nov;100(11):2091-2096. doi: 10.1111/aogs.14246. PMID: 34486103.
• Oxley SG, Mallick R, & Odejinmi F (2019). Laparoscopic myomectomy: an alternative approach to tackling submucous myomas? Journal of Minimally Invasive Gynecology PMID: 309263366
• Mallick R, Oxley SG, Odejinmi F (2019), The use of Ulipristal acetate (Esmya) prior to laparoscopic myomectomy; help or hindrance? Gynecology and Minimally Invasive Therapy, (8),62-66. PMID: 31143625